Protein Alignment MAPK15 and Cdk1

DIOPT Version :10

• Sequence 1: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Sequence 2: NP_476797.1
• Gene: Cdk1 / 34411
• FlyBaseID: FBgn0004106
• Length: 297
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 118/316 - (37%)
• Similarity: 168/316 - (53%)
• Gaps: 53/316 - (16%)

Human    26 YGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTFREITLLQEFGD 90
            ||:|:|..:|.||::||:|||      :.::.|.|   .|.|          ..|||:||:|. .
  Fly    15 YGVVYKGRNRLTGQIVAMKKI------RLESDDEG---VPST----------AIREISLLKEL-K 59

Human    91 HPNIISLLDVIRAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVH-----VRSIFYQLLRATRFLH 150
            |.||:.|.||:..||  .|||:|||:..||...:  ..|..|.|     |||..||:..|..|.|
  Fly    60 HENIVCLEDVLMEEN--RIYLIFEFLSMDLKKYM--DSLPVDKHMESELVRSYLYQITSAILFCH 120

Human   151 SGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHR 215
            ...|:|||.||.|:|:|.:..:|:.||||.||.| :|.    :..|..:.|.|||||||||.|.|
  Fly   121 RRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFG-IPV----RIYTHEIVTLWYRAPEVLLGSPR 180

Human   216 YTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGS--------GCRA 272
            |:..||:||:|||..||...:|||.|.|.:.||..:...:..|:|:....:.|        .|.:
  Fly   181 YSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNTFPCWS 245

Human   273 SVLHQLGSRPRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRF 328
            :  :|| :...:.|||        ..:||::::|::.|..|:||...|:|||...|
  Fly   246 T--NQL-TNQLKNLDA--------NGIDLIQKMLIYDPVHRISAKDILEHPYFNGF 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	118/316 (37%)
Cdk1	NP_476797.1	STKc_CDK1_euk	3..287	CDD:270845	116/311 (37%)