Protein Alignment MAPK15 and rl

DIOPT Version :10

• Sequence 1: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Sequence 2: NP_001015122.1
• Gene: rl / 3354888
• FlyBaseID: FBgn0003256
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 359
• Identity: 142/359 - (39%)
• Similarity: 202/359 - (56%)
• Gaps: 36/359 - (10%)

Human    25 AYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTFREITLLQEFG 89
            |||:|..|.|..|.:.|||||| ..|..:|                   ..|||.||||:|..|
  Fly    48 AYGMVVSADDTLTNQRVAIKKI-SPFEHQT-------------------YCQRTLREITILTRF- 91

Human    90 DHPNIISLLDVIRAEN---DRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHS 151
            .|.|||.:.|::|.::   .||:|:|...|:|||..:::...|..| |:....||:||..:::||
  Fly    92 KHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKTQRLSND-HICYFLYQILRGLKYIHS 155

Human   152 GHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRY 216
            .:|:|||.||||:||:..|.:|:||||||| :.| ||......:|||||||||||||::|:|..|
  Fly   156 ANVLHRDLKPSNLLLNKTCDLKICDFGLAR-IAD-PEHDHTGFLTEYVATRWYRAPEIMLNSKGY 218

Human   217 TLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQLGSR 281
            |..:|:||:||||.|||..||:|||...|.||..||..:..||.:||..:.:....:.|..|..:
  Fly   219 TKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFK 283

Human   282 PRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDEWAREADVRPRAH 346
            |.... |.|.|:....|||||.::|.|.|.||:...:||.|||:::::.|.||...|...|...
  Fly   284 PNVPW-AKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINM- 346

Human   347 EGVQLSVPEYRSRVYQMILECGGSSGTSREKGPE 380
            |...:|....:|.:::..|:       .:|:.|:
  Fly   347 ENDDISRDALKSLIFEETLK-------FKERQPD 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	139/341 (41%)
rl	NP_001015122.1	STKc_ERK1_2_like	32..366	CDD:270839	139/343 (41%)