Protein Alignment MAPK15 and spk1

DIOPT Version :9

• Sequence 1: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Sequence 2: NP_594009.1
• Gene: spk1 / 2542474
• PomBaseID: SPAC31G5.09c
• Length: 372
• Species: Schizosaccharomyces pombe
• Alignment Length: 313
• Identity: 142/313 - (45%)
• Similarity: 187/313 - (59%)
• Gaps: 28/313 - (8%)

Human    25 AYGIVWKAVDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTFREITLLQEFG 89
            |||:|..|:.:.:|..||:|||.                  |.:.|||  ..||.|||.||:.|
pombe    49 AYGVVCAALHKPSGLKVAVKKIH------------------PFNHPVF--CLRTLREIKLLRHF- 92

Human    90 DHPNIISLLDVI---RAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLHS 151
            .|.||||:||::   ..:...|:|:|.|.|:|||..|||...|..| |.:...||:|||.:.:||
pombe    93 RHENIISILDILPPPSYQELEDVYIVQELMETDLYRVIRSQPLSDD-HCQYFTYQILRALKAMHS 156

Human   152 GHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQAVTEYVATRWYRAPEVLLSSHRY 216
            ..|||||.||||:||:|||.:|:.|||||||  ...:|.....:|||||||||||||::||...|
pombe   157 AGVVHRDLKPSNLLLNANCDLKVADFGLARS--TTAQGGNPGFMTEYVATRWYRAPEIMLSFREY 219

Human   217 TLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQLGSR 281
            :..:|:||.||||.|||..||||||.....|:.|||..:..|:.:|...:.|......:..|...
pombe   220 SKAIDLWSTGCILAEMLSARPLFPGKDYHSQITLILNILGTPTMDDFSRIKSARARKYIKSLPFT 284

Human   282 PRQTLDALLPPDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDE 334
            |:.:..||. |..||:|:|||.:||.|.||||::|.:||:||||..:|..|||
pombe   285 PKVSFKALF-PQASPDAIDLLEKLLTFNPDKRITAEEALKHPYVAAYHDASDE 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	142/313 (45%)
		S_TKc	25..325	CDD:214567	136/302 (45%)
spk1	NP_594009.1	STKc_ERK1_2_like	33..371	CDD:270839	142/313 (45%)
		S_TKc	39..327	CDD:214567	136/302 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000164
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810