DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment MAPK15 and pmk1

DIOPT Version :9

Sequence 1:XP_011515227.1 Gene:MAPK15 / 225689 HGNCID:24667 Length:565 Species:Homo sapiens
Sequence 2:NP_595289.1 Gene:pmk1 / 2539920 PomBaseID:SPBC119.08 Length:422 Species:Schizosaccharomyces pombe


Alignment Length:321 Identity:139/321 - (43%)
Similarity:187/321 - (58%) Gaps:39/321 - (12%)


- Green bases have known domain annotations that are detailed below.


Human    25 AYGIVWKA--VDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTFREITLLQE 87
            |||||..|  |..:..|.||||||.:.|...                   :..:|..|||.||..
pombe    31 AYGIVCAARNVASKDQEAVAIKKITNVFSKS-------------------ILTKRALREIKLLIH 76

Human    88 FGDHPNIISL--LDVIRAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLH 150
            |.:|.||..:  ||:|...|..::|:..|.|:.||||:|:.|..|.|.|.:|..||:|...:::|
pombe    77 FRNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKSGQPLTDAHFQSFIYQILCGLKYIH 141

Human   151 SGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQA--VTEYVATRWYRAPEVLLSS 213
            |.:|:|||.||.|:|::|:|.:|:|||||||...   |.||:..  :|||||||||||||::||.
pombe   142 SANVIHRDLKPGNLLVNADCELKICDFGLARGCS---ENPEENPGFMTEYVATRWYRAPEIMLSF 203

Human   214 HRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQL 278
            ..|..|:|:||:||||.|:|.|.|||.|...:|||.|||..:..|.||.|..:.|. ||.  ..:
pombe   204 SSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEETLSHISSS-RAQ--EYV 265

Human   279 GSRPRQTLDALLP-----PDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDE 334
            .|.|:|   ..:|     |..:|.|||||.:||.|.|::|:|...||:|||:..:|.||||
pombe   266 RSLPKQ---RPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDALEHPYLAVWHDPSDE 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MAPK15XP_011515227.1 STKc_MAPK15-like 25..364 CDD:270841 139/321 (43%)
S_TKc 25..325 CDD:214567 133/310 (43%)
pmk1NP_595289.1 STKc_MPK1 20..351 CDD:173750 139/321 (43%)
S_TKc 21..314 CDD:214567 133/310 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0660
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000164
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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