Protein Alignment MAPK15 and pmk1

DIOPT Version :10

• Sequence 1: XP_011515227.1
• Gene: MAPK15 / 225689
• HGNCID: 24667
• Length: 565
• Species: Homo sapiens
• Sequence 2: NP_595289.1
• Gene: pmk1 / 2539920
• PomBaseID: SPBC119.08
• Length: 422
• Species: Schizosaccharomyces pombe
• Alignment Length: 321
• Identity: 139/321 - (43%)
• Similarity: 187/321 - (58%)
• Gaps: 39/321 - (12%)

Human    25 AYGIVWKA--VDRRTGEVVAIKKIFDAFRDKTDAQDMGFLLAPPTHTPVFLSLQRTFREITLLQE 87
            |||||..|  |..:..|.||||||.:.|...                   :..:|..|||.||..
pombe    31 AYGIVCAARNVASKDQEAVAIKKITNVFSKS-------------------ILTKRALREIKLLIH 76

Human    88 FGDHPNIISL--LDVIRAENDRDIYLVFEFMDTDLNAVIRKGGLLQDVHVRSIFYQLLRATRFLH 150
            |.:|.||..:  ||:|...|..::|:..|.|:.||||:|:.|..|.|.|.:|..||:|...:::|
pombe    77 FRNHRNITCIYDLDIINPYNFNEVYIYEELMEADLNAIIKSGQPLTDAHFQSFIYQILCGLKYIH 141

Human   151 SGHVVHRDQKPSNVLLDANCTVKLCDFGLARSLGDLPEGPEDQA--VTEYVATRWYRAPEVLLSS 213
            |.:|:|||.||.|:|::|:|.:|:|||||||...   |.||:..  :|||||||||||||::||.
pombe   142 SANVIHRDLKPGNLLVNADCELKICDFGLARGCS---ENPEENPGFMTEYVATRWYRAPEIMLSF 203

Human   214 HRYTLGVDMWSLGCILGEMLRGRPLFPGTSTLHQLELILETIPPPSEEDLLALGSGCRASVLHQL 278
            ..|..|:|:||:||||.|:|.|.|||.|...:|||.|||..:..|.||.|..:.|. ||.  ..:
pombe   204 SSYHKGIDVWSVGCILAELLGGTPLFKGKDFVHQLNLILHQLGTPDEETLSHISSS-RAQ--EYV 265

Human   279 GSRPRQTLDALLP-----PDTSPEALDLLRRLLVFAPDKRLSATQALQHPYVQRFHCPSDE 334
            .|.|:|   ..:|     |..:|.|||||.:||.|.|::|:|...||:|||:..:|.||||
pombe   266 RSLPKQ---RPIPFETNFPKANPLALDLLAKLLAFDPNRRISVDDALEHPYLAVWHDPSDE 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAPK15	XP_011515227.1	STKc_MAPK15-like	25..364	CDD:270841	139/321 (43%)
pmk1	NP_595289.1	STKc_MPK1	20..351	CDD:173750	139/321 (43%)