Protein Alignment FGB and CG30280

DIOPT Version :10

• Sequence 1: NP_005132.2
• Gene: FGB / 2244
• HGNCID: 3662
• Length: 491
• Species: Homo sapiens
• Sequence 2: NP_611641.6
• Gene: CG30280 / 37522
• FlyBaseID: FBgn0050280
• Length: 288
• Species: Drosophila melanogaster
• Alignment Length: 304
• Identity: 101/304 - (33%)
• Similarity: 147/304 - (48%)
• Gaps: 50/304 - (16%)

Human   185 ETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGG 249
            ||:  |:..||..:....||..|.:|    :...|:|   |..|::.:..|:....|   :..|.
  Fly    23 ETL--NLFGNLEAIYEQAENALSTLQ----ESLLQLE---TNGTLNTSPDVIYPTSC---LTSGD 75

Human   250 ETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKN 314
            ..:.::.::. ..:.|::|||:......||.|||.|..|::.|.|.|..||.||||
  Fly    76 LENGLHTLKV-PGLSPFQVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGN--------- 130

Human   315 YCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVK-AHYGGFTVQNEANKYQI-SVNKYRG 377
               |..||:||.:||..||.:.|.||.:.:||: .|.:| |.:..|.:.||.:.|.: ::.||.|
  Fly   131 ---LMDEYFLGLEKIRALTALEPHELYVHLEDF-DDTIKHAKFDEFAIGNEDDDYAMNTLGKYSG 191

Human   378 TAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANP 442
            |||::|..              |..|.|||||||||    .:..|.|:....||||||.|..:|.
  Fly   192 TAGDSLRS--------------HRKMKFSTYDRDND----HEFNKNCAFYYLGGWWYNACLDSNL 238

Human   443 NGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRP 486
            ||:|..||:|...:...    |:.|.:|:|..|..|...|.|||
  Fly   239 NGQYMPGGKYEESLFAR----GMCWRSWRGHNYGYRVTQMMIRP 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGB	NP_005132.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..75
		Beta-chain polymerization, binding distal domain of another fibrin	45..47
		Fib_alpha	91..234	CDD:462570	13/48 (27%)
		Fibrinogen_C	237..486	CDD:395095	85/250 (34%)
CG30280	NP_611641.6	FReD	65..279	CDD:238040	87/253 (34%)