DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment FGB and CG1791

DIOPT Version :10

Sequence 1:NP_005132.2 Gene:FGB / 2244 HGNCID:3662 Length:491 Species:Homo sapiens
Sequence 2:NP_572591.1 Gene:CG1791 / 31927 FlyBaseID:FBgn0030163 Length:334 Species:Drosophila melanogaster


Alignment Length:379 Identity:99/379 - (26%)
Similarity:162/379 - (42%) Gaps:87/379 - (22%)


- Green bases have known domain annotations that are detailed below.


Human   123 IRNSVDEL----NNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKDNENVVNEYSSELEKHQLYI 183
            :|||.:..    |:.......|.:.....:..:.|..|..:.::.:.:.::.||.::        
  Fly    32 MRNSAEPFLLAENDTASCPVSTLAGLAARVQFMTDELQNLKTELNELQGLIEEYKNQ-------- 88

Human   184 DETVNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKG 248
                .:.||...|:||.    |.:.:|.....::       ||       |..:.:.|.:  .|.
  Fly    89 ----GTGIPIATRLLRP----LPASVQTFPLALA-------TP-------PDDTPRNCYD--EKH 129

Human   249 GETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGK 313
            |:.  ...|.||  ::|:...||....:|||.||..|.|||.||.:.|..||.|||         
  Fly   130 GQV--RIRIAPD--MEPFFASCDQKVRDGGWMVIAYRFDGSEDFNKDWQNYKAGFG--------- 181

Human   314 NYCGLPGEYWLGNDKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISV-NKYRG 377
               .|..|:::|.||:.:||.....||||.|:...|::..|.|..|::.:|:.||.:.| ..|:|
  Fly   182 ---ALNSEFFIGLDKLHRLTNSEHHELLIIMKKKSGEERFALYDHFSIGSESEKYLLYVLGAYKG 243

Human   378 TAGNALMDGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNR-CHAAN 441
            .||::|              ..|.|..|:|:|:|||     |..:.|::...|.|||.| |..:|
  Fly   244 DAGDSL--------------RYHAGKKFTTFDQDND-----DNGQNCARTHAGAWWYGRECFESN 289

Human   442 PNGRYYWGGQYTWDMAKHGTD----DGVVWMNW-KGSWYSMRKMSMKIRPFFPQ 490
            ..|.:         .:|:|.:    .|::|.:: .|...|:..:.|.|||...|
  Fly   290 LFGTF---------QSKYGQEIGYFKGILWKSFLPGPTGSLSYVRMLIRPLKKQ 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FGBNP_005132.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 44..75
Beta-chain polymerization, binding distal domain of another fibrin 45..47
Fib_alpha 91..234 CDD:462570 18/114 (16%)
Fibrinogen_C 237..486 CDD:395095 77/255 (30%)
CG1791NP_572591.1 FReD 119..331 CDD:238040 78/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.