Protein Alignment FGB and CG30281

DIOPT Version :10

• Sequence 1: NP_005132.2
• Gene: FGB / 2244
• HGNCID: 3662
• Length: 491
• Species: Homo sapiens
• Sequence 2: NP_726164.1
• Gene: CG30281 / 246525
• FlyBaseID: FBgn0050281
• Length: 291
• Species: Drosophila melanogaster
• Alignment Length: 291
• Identity: 91/291 - (31%)
• Similarity: 144/291 - (49%)
• Gaps: 55/291 - (18%)

Human   200 SILENLRSKIQKLE---SDVSAQMEYCRTPCTVSCNIPVVSGKECEEIIRKGGETSEMYLIQPDS 261
            |::.:|:.::::|:   .:::.:.....|....||             :..|..::.:::|:. .
  Fly    34 SMVSSLKIRLEELKQSYKEITEERGSHETINPSSC-------------LAAGINSNGIHVIEV-P 84

Human   262 SVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGN 326
            .::|:.||||......||||||.|||||.:|.|.|:.|.||||.            |.||:::|.
  Fly    85 GLEPFPVYCDTRLAGSGWTVIQRRQDGSENFYRCWEEYSQGFGE------------LSGEFFMGL 137

Human   327 DKISQLTRMGPTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISV-NKYRGTAGNALMDGASQL 390
            :|:..||...|.||.:.|||:.|....|.|..|.:.|.:..|.:|| .||.|.||::|
  Fly   138 EKLHFLTTAEPYELFVYMEDFNGVVHDARYEDFAIGNASASYALSVLGKYSGDAGDSL------- 195

Human   391 MGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWD 455
                   ..|.||.|||:|.|:.|       ..|::...|.|||::|..:|.||:|..||::...
  Fly   196 -------RYHKGMPFSTFDHDDTG-------HGCARIYVGAWWYDQCQRSNLNGQYLEGGRFEPK 246

Human   456 MAKHGTDDGVVWMNWKGSWYSMRKMSMKIRP 486
            |:..    |:.||:|:|..|..:.:.|.|||
  Fly   247 MSGR----GITWMSWRGYDYGYKFVQMMIRP 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGB	NP_005132.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..75
		Beta-chain polymerization, binding distal domain of another fibrin	45..47
		Fib_alpha	91..234	CDD:462570	6/36 (17%)
		Fibrinogen_C	237..486	CDD:395095	83/249 (33%)
CG30281	NP_726164.1	FReD	63..274	CDD:238040	87/262 (33%)