Protein Alignment FGA and CG30280

DIOPT Version :10

• Sequence 1: NP_000499.1
• Gene: FGA / 2243
• HGNCID: 3661
• Length: 866
• Species: Homo sapiens
• Sequence 2: NP_611641.6
• Gene: CG30280 / 37522
• FlyBaseID: FBgn0050280
• Length: 288
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 99/272 - (36%)
• Similarity: 146/272 - (53%)
• Gaps: 38/272 - (13%)

Human   601 YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSG------TQSGIFNIKLPGSSKIF 659
            |:.|:.|.|............|...:.|     ||:  :|:.      .::|:..:|:||.|. |
  Fly    35 YEQAENALSTLQESLLQLETNGTLNTSP-----DVI--YPTSCLTSGDLENGLHTLKVPGLSP-F 91

Human   660 SVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQ-RGSV 723
            .|||:.:.:..||::||:|..|:|:|.|.|::||.|||:|.|    |::||.:.:..||. ....
  Fly    92 QVYCENQLAGPGWIVIQKRFSGNLSFFRNWKEYKNGFGNLMD----EYFLGLEKIRALTALEPHE 152

Human   724 LRVELEDWAGNEAYAEY-HFRVGSEAEGYALQ-VSSYEGTAGDALIEGSVEEGAEYTSHNNMQFS 786
            |.|.|||:.....:|:: .|.:|:|.:.||:. :..|.|||||:|           .||..|:||
  Fly   153 LYVHLEDFDDTIKHAKFDEFAIGNEDDDYAMNTLGKYSGTAGDSL-----------RSHRKMKFS 206

Human   787 TFDRDAD-QWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGAD 850
            |:|||.| ::.:|||..|.||||||.|..:||||.|.|||.|:..     ....|:.|.|:||.:
  Fly   207 TYDRDNDHEFNKNCAFYYLGGWWYNACLDSNLNGQYMPGGKYEES-----LFARGMCWRSWRGHN 266

Human   851 YSLRAVRMKIRP 862
            |..|..:|.|||
  Fly   267 YGYRVTQMMIRP 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGA	NP_000499.1	Alpha-chain polymerization, binding distal domain of another fibrin gamma chain	36..38
		Fib_alpha	49..191	CDD:462570
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..460
		Fibrinogen_aC	445..509	CDD:432370
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..638		8/36 (22%)
		FReD	630..863	CDD:238040	93/243 (38%)
CG30280	NP_611641.6	FReD	65..279	CDD:238040	91/237 (38%)