Protein Alignment FGA and CG6788

DIOPT Version :10

• Sequence 1: NP_000499.1
• Gene: FGA / 2243
• HGNCID: 3661
• Length: 866
• Species: Homo sapiens
• Sequence 2: NP_573254.1
• Gene: CG6788 / 32773
• FlyBaseID: FBgn0030880
• Length: 358
• Species: Drosophila melanogaster
• Alignment Length: 235
• Identity: 90/235 - (38%)
• Similarity: 123/235 - (52%)
• Gaps: 37/235 - (15%)

Human   638 THPSGTQSGIFNIK---LPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSL 699
            |.|...:.||:.:|   ||.    |...|    |..|||.||:|.||:.||:|.|:|||.|||.:
  Fly   152 TCPIDGKGGIYKLKIRELPA----FEAPC----SSNGWLTIQKRYDGAENFDRGWKDYKDGFGRV 208

Human   700 NDEGEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQ-VSSYEGT 761
                .|||::|.:.:||:| ||...|.::|....|..::|.| :|.:|.|.|.|.|: :..|.||
  Fly   209 ----RGEFFIGLEKVHLMTRQRRHELYIKLGKIDGTTSHAHYDNFELGGEIESYELKSLGRYNGT 269

Human   762 AGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGS 826
            |||:|           ..|...:|:|.|:|.|.:..|||....|||||.:|..:.|||.:|..|.
  Fly   270 AGDSL-----------RPHERQKFTTNDKDNDAYRFNCAADEYGGWWYYDCAKSMLNGKFYKEGR 323

Human   827 YDPRNNSPYEIENGVVWVSFRGAD--YSLRAVRMKIRPLV 864
              .||..    .||::|.|:...|  |||..|.|.|||.:
  Fly   324 --SRNGK----TNGILWGSWHNNDWTYSLTFVEMMIRPRI 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGA	NP_000499.1	Alpha-chain polymerization, binding distal domain of another fibrin gamma chain	36..38
		Fib_alpha	49..191	CDD:462570
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..460
		Fibrinogen_aC	445..509	CDD:432370
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..638		90/235 (38%)
		FReD	630..863	CDD:238040	89/232 (38%)
CG6788	NP_573254.1	FReD	160..356	CDD:238040	87/224 (39%)