Protein Alignment FGA and CG1791

DIOPT Version :10

• Sequence 1: NP_000499.1
• Gene: FGA / 2243
• HGNCID: 3661
• Length: 866
• Species: Homo sapiens
• Sequence 2: NP_572591.1
• Gene: CG1791 / 31927
• FlyBaseID: FBgn0030163
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 94/247 - (38%)
• Similarity: 126/247 - (51%)
• Gaps: 41/247 - (16%)

Human   636 LQTHPSGT-------QSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYK 693
            |.|.|..|       :.|...|::....:.|...|||:...|||::|..|.|||.:||:.||:||
  Fly   113 LATPPDDTPRNCYDEKHGQVRIRIAPDMEPFFASCDQKVRDGGWMVIAYRFDGSEDFNKDWQNYK 177

Human   694 RGFGSLNDEGEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQV- 755
            .|||:||    .||::|.|.||.|| .....|.:.::..:|.|.:|.| ||.:|||:|.|.|.|
  Fly   178 AGFGALN----SEFFIGLDKLHRLTNSEHHELLIIMKKKSGEERFALYDHFSIGSESEKYLLYVL 238

Human   756 SSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWY-NNCQAANLNG 819
            .:|:|.|||:|         .|  |...:|:|||:|.|...:|||..:.|.||| ..|..:||.|
  Fly   239 GAYKGDAGDSL---------RY--HAGKKFTTFDQDNDDNGQNCARTHAGAWWYGRECFESNLFG 292

Human   820 IYYPGGSYDPRNNSPYEIE----NGVVWVSF-RGADYSLRAVRMKIRPLVTQ 866
            .:          .|.|..|    .|::|.|| .|...||..|||.||||..|
  Fly   293 TF----------QSKYGQEIGYFKGILWKSFLPGPTGSLSYVRMLIRPLKKQ 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGA	NP_000499.1	Alpha-chain polymerization, binding distal domain of another fibrin gamma chain	36..38
		Fib_alpha	49..191	CDD:462570
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..460
		Fibrinogen_aC	445..509	CDD:432370
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	543..638		1/1 (100%)
		FReD	630..863	CDD:238040	91/242 (38%)
CG1791	NP_572591.1	FReD	119..331	CDD:238040	88/236 (37%)