Protein Alignment FES and LSB1

DIOPT Version :9

• Sequence 1: NP_001996.1
• Gene: FES / 2242
• HGNCID: 3657
• Length: 822
• Species: Homo sapiens
• Sequence 2: NP_011652.1
• Gene: LSB1 / 853037
• SGDID: S000003368
• Length: 241
• Species: Saccharomyces cerevisiae
• Alignment Length: 70
• Identity: 15/70 - (21%)
• Similarity: 23/70 - (32%)
• Gaps: 26/70 - (37%)

Human   753 TFSLGASPYPNLSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQR-------PSFSTI 810
            ::...||.||  |.|.:..:....|.:..|                 .|.|:       |.|:..
Yeast   137 SYEPAASQYP--SQQVSAPYAPPAGYMQAP-----------------PPQQQQAPLPYPPPFTNY 182

Human   811 YQELQ 815
            ||:.|
Yeast   183 YQQPQ 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FES	NP_001996.1	Important for interaction with membranes containing phosphoinositides	1..300
		F-BAR_Fes	7..239	CDD:153369
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	394..421
		SH2_Fps_family	453..537	CDD:198224
		Pkinase_Tyr	561..814	CDD:285015	14/67 (21%)
		PTKc_Fes	564..815	CDD:270667	14/68 (21%)
LSB1	NP_011652.1	SH3	55..108	CDD:214620
		PRK14971	<100..>156	CDD:237874	6/20 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000