Protein Alignment FES and skb5

DIOPT Version :9

• Sequence 1: NP_001996.1
• Gene: FES / 2242
• HGNCID: 3657
• Length: 822
• Species: Homo sapiens
• Sequence 2: NP_588016.1
• Gene: skb5 / 2539237
• PomBaseID: SPCC24B10.13
• Length: 140
• Species: Schizosaccharomyces pombe
• Alignment Length: 107
• Identity: 22/107 - (20%)
• Similarity: 34/107 - (31%)
• Gaps: 20/107 - (18%)

Human   256 QPEAEYQGFLRQYGSAPDVPPCVTFDESLLEEGEPLEPGELQLNELTVESVQHTLTSVTDELAVA 320
            :.|.:|....|.|...||......|...::||.|         .....::...|:....|..::.
pombe     4 ETEEDYLVVGRDYLYPPDHELHYGFHARVIEEEE---------ERFVDDTFDETIEGSDDSESID 59

Human   321 TEMVFRRQEMVTQLQQELRNEEENTHPRERVQLLGKRQVLQE 362
            ...||...|           |.|:|||.....:|.....|.:
pombe    60 DTEVFYDAE-----------ESESTHPSASFNVLADAVALYD 90

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FES	NP_001996.1	Important for interaction with membranes containing phosphoinositides	1..300		10/43 (23%)
		F-BAR_Fes	7..239	CDD:153369
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	394..421
		SH2_Fps_family	453..537	CDD:198224
		Pkinase_Tyr	561..814	CDD:285015
		PTKc_Fes	564..815	CDD:270667
skb5	NP_588016.1	SH3_Nbp2-like	84..138	CDD:212799	1/7 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000