| Sequence 1: | NP_001996.1 | Gene: | FES / 2242 | HGNCID: | 3657 | Length: | 822 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_034324.2 | Gene: | Fes / 14159 | MGIID: | 95514 | Length: | 822 | Species: | Mus musculus |
| Alignment Length: | 822 | Identity: | 745/822 - (90%) |
|---|---|---|---|
| Similarity: | 783/822 - (95%) | Gaps: | 0/822 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MGFSSELCSPQGHGVLQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMSLQDSGGQSRAISP 65
Human 66 DSPISQSWAEITSQTEGLSRLLRQHAEDLNSGPLSKLSLLIRERQQLRKTYSEQWQQLQQELTKT 130
Human 131 HSQDIEKLKSQYRALARDSAQAKRKYQEASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRAAQL 195
Human 196 HHQHHHQLLLPGLLRSLQDLHEEMACILKEILQEYLEISSLVQDEVVAIHREMAAAAARIQPEAE 260
Human 261 YQGFLRQYGSAPDVPPCVTFDESLLEEGEPLEPGELQLNELTVESVQHTLTSVTDELAVATEMVF 325
Human 326 RRQEMVTQLQQELRNEEENTHPRERVQLLGKRQVLQEALQGLQVALCSQAKLQAQQELLQTKLEH 390
Human 391 LGPGEPPPVLLLQDDRHSTSSSEQEREGGRTPTLEILKSHISGIFRPKFSLPPPLQLIPEVQKPL 455
Human 456 HEQLWYHGAIPRAEVAELLVHSGDFLVRESQGKQEYVLSVLWDGLPRHFIIQSLDNLYRLEGEGF 520
Human 521 PSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNT 585
Human 586 LVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRT 650
Human 651 EGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAA 715
Human 716 SGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLSNQQTREFVEKGGRLP 780
Human 781 CPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKRHR 822 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| FES | NP_001996.1 | Important for interaction with membranes containing phosphoinositides | 1..300 | 265/298 (89%) | |
| F-BAR_Fes | 7..239 | CDD:153369 | 207/231 (90%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 394..421 | 23/26 (88%) | |||
| SH2_Fps_family | 453..537 | CDD:198224 | 75/83 (90%) | ||
| Pkinase_Tyr | 561..814 | CDD:285015 | 244/252 (97%) | ||
| PTKc_Fes | 564..815 | CDD:270667 | 242/250 (97%) | ||
| Fes | NP_034324.2 | Important for interaction with membranes containing phosphoinositides. /evidence=ECO:0000250 | 1..300 | 265/298 (89%) | |
| F-BAR_Fes | 7..239 | CDD:153369 | 207/231 (90%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 392..420 | 23/27 (85%) | |||
| SH2_Fps_family | 453..537 | CDD:198224 | 75/83 (90%) | ||
| PKc_like | 564..814 | CDD:389743 | 241/249 (97%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83974320 | |
| Domainoid | 1 | 1.000 | 806 | 1.000 | Domainoid score | I2800 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0194 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H37563 | |
| Inparanoid | 1 | 1.050 | 1506 | 1.000 | Inparanoid score | I2986 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S3720 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG47024 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000006 | |
| OrthoInspector | 1 | 1.000 | - | - | oto113675 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100013 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR24418 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3894 |
| SonicParanoid | 1 | 1.000 | - | - | X1749 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 18 | 18.240 | |||||