DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wnt3a and Wnt10

DIOPT Version :9

Sequence 1:NP_033548.1 Gene:Wnt3a / 22416 MGIID:98956 Length:352 Species:Mus musculus
Sequence 2:NP_609109.3 Gene:Wnt10 / 34011 FlyBaseID:FBgn0031903 Length:483 Species:Drosophila melanogaster


Alignment Length:402 Identity:140/402 - (34%)
Similarity:191/402 - (47%) Gaps:105/402 - (26%)


- Green bases have known domain annotations that are detailed below.


Mouse    42 CASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVS----NSLAIFGPVL 102
            |.|:|||...|:..|....::..:..||:...|:|||.||:..||||:::|    |..|  ..:|
  Fly    76 CRSVPGLTKDQVELCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHA--SSLL 138

Mouse   103 DKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQG----------------------- 144
            .|..|||||..||::||||.:|.|:|::|....|||...:..                       
  Fly   139 KKGYRESAFAFAISAAGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLE 203

Mouse   145 -----SPGE-----------GWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQ 193
                 :|.|           .|||||||.:::||...|:.|.|.||...|.:|.:|.|||.|||.
  Fly   204 TNQILTPEEEKKYERSKIASRWKWGGCSHNMDFGVEYSKLFLDCREKAGDIQSKINLHNNHAGRI 268

Mouse   194 AIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSA----------SEMVV----E 244
            |::::|..:|||||:||||::||||.|.|||..:|..||.::..|          .|.||    .
  Fly   269 AVSNNMEFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVVVLKRA 333

Mouse   245 KHRESRGW--------------------------VETLR------PRYTYFKVPT---------- 267
            ::::|.|.                          .||.|      .|.|  :.|:          
  Fly   334 RNKKSNGGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGT--RQPSADKNAARMAR 396

Mouse   268 --ERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCV 330
              |..|.||:.||||||.:......||..|.||.::...|||..|||||||:...:||.|:|||.
  Fly   397 KLETSLFYYQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAERCHCK 461

Mouse   331 FHWCCYVSCQEC 342
            |.|||.|.|:||
  Fly   462 FQWCCNVECEEC 473

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wnt3aNP_033548.1 Wnt_Wnt3_Wnt3a 39..352 CDD:381709 140/402 (35%)
Wnt10NP_609109.3 wnt 82..466 CDD:278536 130/387 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167842322
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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