Protein Alignment Wnt10b and Wnt5

DIOPT Version :9

• Sequence 1: NP_035848.1
• Gene: Wnt10b / 22410
• MGIID: 108061
• Length: 389
• Species: Mus musculus
• Sequence 2: NP_001285407.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Alignment Length: 505
• Identity: 129/505 - (25%)
• Similarity: 178/505 - (35%)
• Gaps: 211/505 - (41%)

Mouse    48 CLTLSGLSKRQLGLCLRSPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGG---GRLPHHSAI 109
            |.:..|||..|...|::...|..:..:|...|:.|||.|.:::|||||.....   |.:...:|
  Fly   548 CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAA- 611

Mouse   110 LKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKTFP 174
                 .|.||..::.||.|...:|.||..|:|.||.|                     |||
  Fly   612 -----PEMAFIHALAAATVTSFIARACRDGQLASCSC---------------------SRG---- 646

Mouse   175 ISQPSPVPGSVPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREA-------------------- 219
             |:|..:         .|.|:||||..:::|..||:.||:||||.
  Fly   647 -SRPKQL---------HDDWKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREEINKNR 701

Mouse   220 ----------------------------------------------------------------- 219
                                                                             
  Fly   702 MHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRITKEILT 766

Mouse   220 ------------------------------------------------PRD-------------- 222
                                                            ||:
  Fly   767 SKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDGGILPR 831

Mouse   223 ----IQAR--MRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAIGAALRERLSR 281
                ::||  |.:|||..||:.|.:..:..|||||.||||...|||:.....|.||..|||:...
  Fly   832 STATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREKYEG 896

Mouse   282 AIFIDTHNRNSGAFQPRLRPRRL------SGELVYFEKSPDFCERDPTLGSPGTRGRACNKTSRL 340
            |..:..:.|.      ||:.:.|      :.:|:|.::|||:|.....|..|||.||.|:|.|..
  Fly   897 ATKVKINKRG------RLQIKDLQFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKNSSG 955

Mouse   341 LDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDEC-KVTEWVNVCK 389
            |:.|..||||||:|.......|||:|:|||||.|.|:.| ||.| .:.||
  Fly   956 LESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLE-EHTCK 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10b	NP_035848.1	Wnt_Wnt10b	45..389	CDD:381730	127/503 (25%)
Wnt5	NP_001285407.1	wnt	554..1004	CDD:278536	125/497 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842342
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740