Protein Alignment FER and fer

DIOPT Version :9

• Sequence 1: XP_011541568.1
• Gene: FER / 2241
• HGNCID: 3655
• Length: 837
• Species: Homo sapiens
• Sequence 2: XP_012818421.1
• Gene: fer / 549656
• XenbaseID: XB-GENE-1015488
• Length: 822
• Species: Xenopus tropicalis
• Alignment Length: 837
• Identity: 667/837 - (79%)
• Similarity: 753/837 - (89%)
• Gaps: 15/837 - (1%)

Human     1 MGFGSDLKNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQMNYVS 65
            ||||.:|::||:|:||||||||||||||||||||||||||||||||||||||:||||.:.::|:|
 Frog     1 MGFGKELRSSHDALLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQMDKESALPLDYIS 65

Human    66 NVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQIEAEMIKVTK 130
            |||.|||.::|||||||:|||||||:||:|||||||.:|||||.|||||..:||||||||.||:|
 Frog    66 NVSNSWLHLVQQTEQLSKIMKTHAEELNAGPLHRLTTLIKDKQHVKKSYNNIHQQIEAEMNKVSK 130

Human   131 TELEKLKCSYRQLIKEMNSAKEKYKEALAKGKETEKAKERYDKATMKLHMLHNQYVLALKGAQLH 195
            |||||||.||:||.||:||||||:|:|..||||||||::|||||.||||:||||||||:||||||
 Frog   131 TELEKLKSSYKQLTKEVNSAKEKFKDASTKGKETEKARDRYDKANMKLHILHNQYVLAVKGAQLH 195

Human   196 QNQYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEY 260
            |:||||.|||||||||||||||||:||||||.||.||||||:||||.||||::..||:|:|||||
 Frog   196 QHQYYDSTLPLLLDSLQKMQEEMIQALKGIFAEYCQITSLVSEEIVAVHKELETCVEEINPSTEY 260

Human   261 NNFIDVHRTTAAKEQEIEFDTSLLEENENLQANEIMWNNLTAESLQVMLKTLAEELMQTQQMLLN 325
            .|||:.|||...:|.:||||||||||.|||||||||||||||:||..||||..|||.||||.||.
 Frog   261 ENFIEKHRTEETREPDIEFDTSLLEEIENLQANEIMWNNLTADSLNSMLKTATEELSQTQQSLLT 325

Human   326 KEEAVLELEKRIEESSETCEKKSDIVLLLSQKQALEELKQSVQQLRCTEAKFSAQKELLEQKVQE 390
            |||.:.:||..:|||:.|||||||.|||||||||:||||||::||:|.|:|.||||.||:||:|:
 Frog   326 KEEQLSKLEVNLEESASTCEKKSDAVLLLSQKQAIEELKQSIEQLKCAESKLSAQKMLLDQKIQQ 390

Human   391 NDGKEPPPVVNYEEDARSVTSMERKERLSKFESIRHSIAGIIRSPKSALGSSALSDMISISEKPL 455
            |:|||||||||||||||||.|:::||::|||::.|||||||||||||.||||:|.|.||..||||
 Frog   391 NEGKEPPPVVNYEEDARSVCSVDKKEKVSKFDTFRHSIAGIIRSPKSMLGSSSLLDGISAIEKPL 455

Human   456 AEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTG 520
            :|||||||||||:|||||||:||||||||||||||||||||:||.||||||||:.||.|||||||
 Frog   456 SEQDWYHGAIPRVEAQELLKQQGDFLVRESHGKPGEYVLSVFSDSQRRHFIIQFADNQYRFEGTG 520

Human   521 FSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKKWILSHEDVILGELLGKGNFGEVYKGTLKDK 585
            |..|||||:||||||||||||||||||||:.|||||||:||||.|||||||||||||||||||||
 Frog   521 FPTIPQLIEHHYTTKQVITKKSGVVLLNPVVKDKKWILNHEDVTLGELLGKGNFGEVYKGTLKDK 585

Human   586 TSVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLR 650
            |.|||||||||||||||||||.||:|||||||.||||||||||||||:||:||||.|||||:|||
 Frog   586 TPVAVKTCKEDLPQELKIKFLSEARILKQYDHANIVKLIGVCTQRQPIYIVMELVPGGDFLSFLR 650

Human   651 RKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRLCEGKGEMKETSNLGDLAARNCLVGENNVLKI 715
            :|||::|.|||.|||.|||:||.||||||||||               |||||||||||||||||
 Frog   651 KKKDDMKTKQLAKFSFDAASGMAYLESKNCIHR---------------DLAARNCLVGENNVLKI 700

Human   716 SDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT 780
            ||||||||||.|:||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   701 SDFGMSRQEDDGIYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMT 765

Human   781 NQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKRKLT 837
            |||||||||:||||||||:|||::.:||.|||:|||||||||||:||||::||:|:|
 Frog   766 NQQAREQVEKGYRMSAPQNCPEEVFRIMQKCWEYKPENRPKFSEMQKELSLIKKKIT 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FER	XP_011541568.1	F-BAR_Fer	5..238	CDD:153370	186/232 (80%)
		SH2_Fps_family	453..538	CDD:198224	73/84 (87%)
		Pkinase_Tyr	563..829	CDD:285015	222/265 (84%)
		PKc_like	566..831	CDD:304357	222/264 (84%)
fer	XP_012818421.1	F-BAR_Fer	5..238	CDD:153370	186/232 (80%)
		SH2_Fps_family	453..538	CDD:198224	73/84 (87%)
		PKc_like	566..815	CDD:389743	221/263 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	561	1.000	Domainoid score	I2840
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H74300
Inparanoid	1	1.050	1370	1.000	Inparanoid score	I1727
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG47024
OrthoDB	1	1.010	-	-		D255116at33208
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	1	1.000	-	-		oto155820
Panther	1	1.100	-	-	LDO	PTHR24418
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3894
SonicParanoid	1	1.000	-	-		X1749
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	14.110