DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wnt10a and Wnt5

DIOPT Version :9

Sequence 1:NP_033544.1 Gene:Wnt10a / 22409 MGIID:108071 Length:417 Species:Mus musculus
Sequence 2:NP_001285407.1 Gene:Wnt5 / 32838 FlyBaseID:FBgn0010194 Length:1004 Species:Drosophila melanogaster


Alignment Length:516 Identity:136/516 - (26%)
Similarity:188/516 - (36%) Gaps:207/516 - (40%)


- Green bases have known domain annotations that are detailed below.


Mouse    55 LNANTVCLTLPGLSRRQMEVCVRHPDVAASAIQGIQIAIHECQHQFRDQRWNCSSLETRNKVPYE 119
            ||.|. |.:..|||..|.:.||:|..|..:..:|.:.||.|||.||:::|||||   |.|.....
  Fly   543 LNPNN-CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCS---TTNDETVF 603

Mouse   120 SPIFSRGFRESAFAYAIAAAGVVHAVSNACALGKLKACGCDASRRGDEEAFRRKLHRLQLDALQR 184
            .|:.|....|.||.:|:|||.|...::.||..|:|.:|.|....|      .::||         
  Fly   604 GPMTSLAAPEMAFIHALAAATVTSFIARACRDGQLASCSCSRGSR------PKQLH--------- 653

Mouse   185 GKGLSHGVPEHPAILPASPGLQDSWEWGGCSPDVGFGERFSKDFLDSREP--------------- 234
                                  |.|:||||..::.|..:|:.||:||||.               
  Fly   654 ----------------------DDWKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREE 696

Mouse   235 ------HRD-------------------------------------------------------- 237
                  |.|                                                        
  Fly   697 INKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRIT 761

Mouse   238 ----------------------------------------------------------------- 237
                                                                             
  Fly   762 KEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDG 826

Mouse   238 ---------IHAR--MRLHNNRVGRQAVMENMRRKCKCHGTSGSCQLKTCWQVTPEFRTVGALLR 291
                     :.||  |.||||..||:||::..|..|||||.||||.|.||||.....|.:|..||
  Fly   827 GILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLR 891

Mouse   292 NRFHRATLIRPHNRNGGQLEPGPAGAPSPAPGTPGLRRRASHSDLVYFEKSPDFCEREPRLDSAG 356
            .::..||.::.:.|...|::......|:            :| ||:|.::|||:|.....|...|
  Fly   892 EKYEGATKVKINKRGRLQIKDLQFKVPT------------AH-DLIYLDESPDWCRNSYALHWPG 943

Mouse   357 TVGRLCNKSSTGPDGCGSMCCGRGHNILRQTRSERCHCRFHWCCFVVCEECRITEWVSVCK 417
            |.||:|:|:|:|.:.|..:|||||:|......:|||:|:|||||.|.||.|........||
  Fly   944 THGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLEEHTCK 1004

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wnt10aNP_033544.1 wnt 67..417 CDD:278536 129/502 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 300..327 3/26 (12%)
Wnt5NP_001285407.1 wnt 554..1004 CDD:278536 129/502 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167842336
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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