Protein Alignment ALDH3A2 and CG6661

DIOPT Version :10

• Sequence 1: NP_001026976.1
• Gene: ALDH3A2 / 224
• HGNCID: 403
• Length: 508
• Species: Homo sapiens
• Sequence 2: NP_648686.3
• Gene: CG6661 / 39556
• FlyBaseID: FBgn0036403
• Length: 581
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 82/422 - (19%)
• Similarity: 166/422 - (39%)
• Gaps: 53/422 - (12%)

Human    20 LRFRLQQLEALRRMVQEREKDI---LTAIAADLCKSEFNVYSQEVITVLGEIDFMLENLPEWVTA 81
            ||.|:..:..|.:...:..:||   ||::.|          :.:.:..|.|:.|.::
  Fly   161 LRLRVFLMMTLSKTADDATRDIRRLLTSLRA----------NADYLEHLSELRFEIQ-------- 207

Human    82 KPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPS-ELSENTAK 145
                 ..:.:....:::|.. |.|..:..:....:.:...|..|: .||.|:..|| |::..:..
  Fly   208 -----GDMNVFPSFHLRPMD-GFVAALAPFESVALSSSLALCPAL-MGNTVLWNPSLEVAPVSYL 265

Human   146 ILAKLLPQYLDQDLYIVINGGVEETTELLKQRFDHIFYTG-NTA--------VGKIVMEAAAKHL 201
            |........|...   |||.........|....|.:.:.| ||.        |.|:|.:...:::
  Fly   266 IFRAFQEAGLPSG---VINFVPANERLFLDTITDAVHFAGLNTQASAAFYRHVHKLVSDRMERYI 327

Human   202 --TPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKET 264
              ..:..|..|::..::.....::.|........:...||...:...:...:|:..::..::.|.
  Fly   328 CFPRLVAECPGQNFHFVHASAKVESVVSATVQAAFGFAGQYANSLSRMYVPSSMWPRLREELVEA 392

Human   265 VKEF-YGENIKESPDYERIINLRHFKRILSLLEGQK---IAFGGETDEAT-RYIAPTVLTDVDPK 324
            .::. .|:.|:...|...::::..|:|:..||:..|   ...||..|::| |::.||::...||.
  Fly   393 TEQLTIGDPIESETDIGAMVHINDFRRMQKLLQRTKNMEQLCGGSCDDSTGRFVDPTIVRVSDPL 457

Human   325 TKVMQEEIFGPILPIVPVK--NVDEAINF-INEREKPLALYVFSHNHKLIKRMIDE--TSSGGVT 384
            ..::.|...||.||:....  :..||:.. .|:....|:..:|:...::|...:::  .|:..:.
  Fly   458 DPLLCEPCCGPFLPVFVYSDDSFSEALKLAANQSRYALSGSIFASQDEVILHCLNQLRMSASNLY 522

Human   385 GNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSF 416
            .|:.....|....||||...||.....|...|
  Fly   523 VNERCTGSTYGLTPFGGNRLSGTNDKSGSAYF 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3A2	NP_001026976.1	ALDH_F3AB	5..444	CDD:143450	82/422 (19%)
CG6661	NP_648686.3	ALDH-SF	68..567	CDD:448367	82/422 (19%)