Protein Alignment Eif4h and eIF4B

DIOPT Version :9

• Sequence 1: NP_291039.1
• Gene: Eif4h / 22384
• MGIID: 1341822
• Length: 248
• Species: Mus musculus
• Sequence 2: NP_001015319.1
• Gene: eIF4B / 3355041
• FlyBaseID: FBgn0020660
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 268
• Identity: 68/268 - (25%)
• Similarity: 118/268 - (44%)
• Gaps: 66/268 - (24%)

Mouse    36 LPTEPPYTAYVGNLPFNTVQGDIDAIFKDLSIRSVRLVR-DKDTDKFKGFCYVEFDEVDSLKEAL 99
            :|.:.|:.||:.||||:..:.|:...|:.:::.|:||.| |.:..:.:||.|||.:..:.|...|
  Fly    74 IPHKAPFIAYINNLPFDANEDDLYEFFEGINLISLRLPREDGENGRSRGFGYVELENREDLIHVL 138

Mouse   100 TYDGALLGDRSLRVDIA-----EGRKQDKGGFGFRKGGPDDRGMGGSRESRGGW--DSRDD-FNS 156
            :.....:..|.:|::::     :.|::....|       |..|..|.....|.|  ||::: .|.
  Fly   139 SLPDPSIKGRRIRIELSNENDQQSRQKSNRRF-------DGFGNNGDNRDSGNWRRDSQNNGSNF 196

Mouse   157 GY-----------------RDDFL---GGRGGSRPGD------RRAGPPMGSRFRDGPPLRGSNM 195
            ||                 |||..   ..|..:||..      ||....:..::|:| .::.::.
  Fly   197 GYSSNFERSFNRERKSLPDRDDVNTPGSWRTSARPQSIDTSPTRREVEQVSEKYREG-RVKIADR 260

Mouse   196 DFREPTEEERAQRPRLQLKPRTVATP----------------LNQVANPNSA-IFGGARP----- 238
            ..||.|.:...:||:|.|||||:..|                |::....:|. :||.|:|
  Fly   261 YSREETSKVEEERPKLNLKPRTLPLPDVKTIEFEKCDVDEFNLDKQGGTSSLNVFGSAKPVDTAA 325

Mouse   239 RE-EVVQK 245
            || |:.|:
  Fly   326 RELEIEQR 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eif4h	NP_291039.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		1/4 (25%)
		RRM_eIF4H	37..120	CDD:409835	24/88 (27%)
		SF-CC1	<40..>227	CDD:273721	58/237 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	122..248		43/176 (24%)
eIF4B	NP_001015319.1	RRM	<72..268	CDD:223796	49/201 (24%)
		RRM_eIF4B	79..155	CDD:240848	23/75 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1292
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940