DRSC/TRiP Functional Genomics Resources

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Protein Alignment Vim and LamC

DIOPT Version :9

Sequence 1:NP_035831.2 Gene:Vim / 22352 MGIID:98932 Length:466 Species:Mus musculus
Sequence 2:NP_001260974.1 Gene:LamC / 36615 FlyBaseID:FBgn0010397 Length:640 Species:Drosophila melanogaster


Alignment Length:474 Identity:138/474 - (29%)
Similarity:228/474 - (48%) Gaps:95/474 - (20%)


- Green bases have known domain annotations that are detailed below.


Mouse    31 VTTSTRTYSLGSALRPSTSRSLYSSSPGGAYVTRSSAVRLRSSVPGVRLLQDSVDFSLADAINTE 95
            ||.:||           .||:..|:..|||    |::.|:.::.|                 .:.
  Fly     6 VTLNTR-----------VSRASTSTPVGGA----STSSRVGATSP-----------------TSP 38

Mouse    96 FKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAEL---EQLKGQGKSRLGDLYEEEMREL 157
            .:.:|..||.|||.||||.|.|||::|.||.:|..|..||   :....:..|.|..:||:|:...
  Fly    39 TRTSRQQEKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRETSNLKAVYEKELAAA 103

Mouse   158 RRQVDQLTNDKARVEV-------ERDNL-------------AEDIMRL----------------- 185
            |:.:|:...:||::|:       |.|:|             ||:..||                 
  Fly   104 RKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKYNQSLA 168

Mouse   186 -REKLQEE----MLQREEAESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHDEEIQEL 245
             |:|.:::    .|:.|.....|...|:.::..:|||:|||.:.:||:||:||..::|.:|:.|.
  Fly   169 DRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQELTET 233

Mouse   246 QAQIQEQHVQIDVDVSK---PDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNND 307
            :::.|.:..:||..:|:   ..|..:|:::|.|||.....|.:|.|..|.::..:|..||||...
  Fly   234 RSRRQIEISEIDGRLSRQYEAKLQQSLQELRDQYEGQMRINREEIELLYDNEIQNLKAAANRAAQ 298

Mouse   308 ALRQAKQESNEYRRQVQSLTCEVDALKGTNESLERQMREMEENFALEAANYQDTIGRLQDEIQNM 372
            ....|.:|....|.::..|..::..|:.||..|..::||:|.....|...:...|..|:.|:|.|
  Fly   299 GSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYIASLEAELQRM 363

Mouse   373 KEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPTFSSLNLRETNLESLPLVDT- 436
            ::|||..|:|||.|:::|::||:|||.|.|||.|||.|:::..|             ..|..|: 
  Fly   364 RDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRLNIESP-------------GRPTTDSG 415

Mouse   437 -HSKRTLLIKTVETRDGQV 454
             .|..:.|..:..:|.|:|
  Fly   416 ISSNGSHLTASASSRSGRV 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
VimNP_035831.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..33 1/1 (100%)
Head 2..95 13/63 (21%)
Filament_head 14..101 CDD:309741 13/69 (19%)
Coil 1A 96..131 18/34 (53%)
Filament 102..410 CDD:306535 115/355 (32%)
Linker 1 132..153 6/23 (26%)
Coil 1B 154..245 32/132 (24%)
Linker 12 246..268 5/24 (21%)
Coil 2 269..407 49/137 (36%)
[IL]-x-C-x-x-[DE] motif. /evidence=ECO:0000250|UniProtKB:P08670 326..329 1/2 (50%)
Tail 408..466 10/49 (20%)
LamCNP_001260974.1 Filament 45..401 CDD:278467 115/355 (32%)
ATP-synt_B <67..>142 CDD:304375 19/74 (26%)
MreC <178..>224 CDD:302802 16/45 (36%)
LTD 473..574 CDD:279300
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0977
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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