DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vax1 and lms

DIOPT Version :9

Sequence 1:	NP_033527.1	Gene:	Vax1 / 22326	MGIID:	1277163	Length:	338	Species:	Mus musculus
Sequence 2:	NP_001286635.1	Gene:	lms / 37322	FlyBaseID:	FBgn0034520	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	87/292 - (29%)
Similarity:	123/292 - (42%)	Gaps:	66/292 - (22%)

- Green bases have known domain annotations that are detailed below.

Mouse    54 SGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILP--KGLDLDRPKRTRTSFTAEQLYRLE 116
            ||...:|..:...||.....|....:.|.|..| ::...  .||..||.||.||:|:|.|:..||
  Fly    39 SGRGGNCLGASRASSPATSSCLDDNMDDGKSDI-DLASDDGNGLGDDRKKRPRTAFSAAQIKALE 102

Mouse   117 MEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELRSVVSETAATCSVLRL 181
            .||:|.:|:...:||.||:||.|:|||:|:||||||||.|:....|       .||.|:....:|
  Fly   103 TEFERGKYLSVAKRTALAKQLQLTETQIKIWFQNRRTKWKRKYTSD-------VETLASHYYAQL 160

Mouse   182 LEQGRLLSPPGLPALLPPCATG----ALGSALRGP----SLPALGAGAAAGSAAAAAAAAA---- 234
                      |:..|..|...|    .......||    |:...|:|:||..|:|..|..:
  Fly   161 ----------GIGGLARPMVVGDRLWLFSQTPTGPTPIQSIMLNGSGSAAPMASATTATGSPMRP 215

Mouse   235 -ATA------PGPA-------GAASQHQPAVGGAP---GPGPAGPGGLHAGAPTASHGLFSLPVP 282
             ||:      |||:       ...::.||.....|   ...|||      |.|.||:      :|
  Fly   216 YATSGGMPPLPGPSVMESARNAILARGQPLNFALPFGVAKPPAG------GVPAASY------IP 268

Mouse   283 SLLGSVASRLSSAPLTMAGSLAGNLQELSARY 314
            .     ....:::.:..|.||..|...|..:|
  Fly   269 R-----CKPYATSYVDYAASLPTNESYLQMKY 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vax1	NP_033527.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69		4/14 (29%)
		Homeobox	103..156	CDD:306543	30/52 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	239..269		8/39 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..338
lms	NP_001286635.1	Cnd2	33..>106	CDD:303063	23/67 (34%)
lms	NP_001286635.1	Homeobox	89..142	CDD:278475	30/52 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847829
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840