Protein Alignment Vars and eEF1gamma

DIOPT Version :9

• Sequence 1: NP_035820.3
• Gene: Vars / 22321
• MGIID: 90675
• Length: 1263
• Species: Mus musculus
• Sequence 2: NP_001189308.1
• Gene: eEF1gamma / 44791
• FlyBaseID: FBgn0029176
• Length: 431
• Species: Drosophila melanogaster
• Alignment Length: 469
• Identity: 127/469 - (27%)
• Similarity: 188/469 - (40%)
• Gaps: 106/469 - (22%)

Mouse     4 LYVSPHPDAFPSLRALIAARYGEA----GDGPGWGGPHPRICLQPPPSSR--TPFPPPRLPALEQ 62
            ||.  :|:.|.:.:|||||:|..|    .|...:|        :...|:.  ..||..::||.|.
  Fly     6 LYT--YPENFRAYKALIAAQYSGAQVKVADNFKFG--------ETNKSAEFLKKFPGGKVPAFET 60

Mouse    63 GPGGLWVWGAPAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTELIPAACGATLPALGLRGPGQD 127
            .. |.::..:.|:|.||....|.|.........||||:|:||.|::||:|....|.||:. |.|.
  Fly    61 AE-GQYLSESNAIAYLLANEQLRGGKCPFVQAQVQQWISFADNEIVPASCAWVFPLLGIL-PQQK 123

Mouse   128 PQAALGALGKALNPLEDWLRLHTYLAGDAPTLADLAAVTALLLPFRYVLDPSARRIWGNVTRWFN 192
            ...|.......|..|...|:..|:|||:..||||:...::||..:.|||:||.|..:|||.|||.
  Fly   124 NSTAKQEAEAVLQQLNQKLQDATFLAGERITLADIVVFSSLLHLYEYVLEPSVRSAFGNVNRWFV 188

Mouse   193 TCVRQPEFRAV-----LGEVALYSGARSVTQ-QPGSEVIAPQKTPAQLKKEAKKREKLEKFQQKQ 251
            |.:.|.:.:||     |.|.||....:...: |..:....||:...|.|:|.|.:||.|..::..
  Fly   189 TILNQKQVQAVVKDYKLCEKALVFDPKKYAEFQAKTGAAKPQQQAQQQKQEKKPKEKKEAPKKAA 253

Mouse   252 KTQQQPPHGEKKPKPEKKEKRDP------GVITYDLPTPPGEKKDVSGAMPDSYSPQYVEAAWYP 310
            :..::....::....|.|.| ||      |...:|........:|.:.::|  |.....:|..|.
  Fly   254 EPAEELDAADEALAAEPKSK-DPFDALPKGTFNFDDFKRVYSNEDEAKSIP--YFFDKFDAENYS 315

Mouse   311 WWERQGFFKPEYGRPSVSAPNPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMR----- 370
            .|..:..:..|..:          |||.|                 |.|.....|..:||
  Fly   316 IWFGEYKYNEELSK----------VFMSC-----------------NLITGMFQRLDKMRKAAFA 353

Mouse   371 --------GETTLWNPGCDHAGIATQVVVEKKLWKERGLNRHQLGREAFL--------EEVWKWK 419
                    |.:|:       :||          |..||.:.      ||.        .||:.||
  Fly   354 SVCLFGEDGNSTI-------SGI----------WVWRGQDL------AFTLSPDWQIDYEVYDWK 395

Mouse   420 AEKGDRIYHQLKKL 433
              |.|....:.|||
  Fly   396 --KLDAKSEETKKL 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vars	NP_035820.3	GST_C_family	92..213	CDD:383119	50/125 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..294		18/82 (22%)
		PTZ00419	281..1263	CDD:240411	34/174 (20%)
		'HIGH' region	343..353		0/9 (0%)
		'KMSKS' region	861..865
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	24/83 (29%)
		GstA	5..187	CDD:223698	66/192 (34%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	48/119 (40%)
		EF1G	271..376	CDD:279041	29/151 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810