DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vars and GstE6

DIOPT Version :9

Sequence 1:	NP_035820.3	Gene:	Vars / 22321	MGIID:	90675	Length:	1263	Species:	Mus musculus
Sequence 2:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	187	Identity:	40/187 - (21%)
Similarity:	73/187 - (39%)	Gaps:	53/187 - (28%)

- Green bases have known domain annotations that are detailed below.

Mouse    53 PPPRLPALEQGPGGLWVWGAPAVAQLLWPAGLGGPGGSRAAVLVQQWVSYADTE-LIP------A 110
            |...:|.||.  .|.::|.:.|:                .|.||.:   |||:: |.|      |
  Fly    51 PQHTVPTLED--DGHYIWDSHAI----------------IAYLVSK---YADSDALYPKDPLKRA 94

Mouse   111 ACGATLP-------ALGLR---------GPGQDPQAALGALGKALNPLEDWLRLHTYLAGDAPTL 159
            .....|.       |.|:|         |..:.|:....|:.:..:.:|.:|:...|:||:..|:
  Fly    95 VVDQRLHFESGVVFANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTI 159

Mouse   160 ADLAAVTALLLPFRYV-LDPSARRIWGNVTRWFNTCVRQPEFRAVLGE-----VALY 210
            ||.:.|:::.....:| ||.:.   :..:..|.....:.|.:....|:     ||::
  Fly   160 ADFSLVSSVASLEAFVALDTTK---YPRIGAWIKKLEQLPYYEEANGKGVRQLVAIF 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vars	NP_035820.3	GST_C_family	92..213	CDD:383119	33/148 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..294
		PTZ00419	281..1263	CDD:240411
		'HIGH' region	343..353
		'KMSKS' region	861..865
GstE6	NP_611328.1	GstA	4..196	CDD:223698	36/168 (21%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	9/43 (21%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	23/120 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810