DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vars and GstE2

DIOPT Version :9

Sequence 1:	NP_035820.3	Gene:	Vars / 22321	MGIID:	90675	Length:	1263	Species:	Mus musculus
Sequence 2:	NP_611324.1	Gene:	GstE2 / 37107	FlyBaseID:	FBgn0063498	Length:	221	Species:	Drosophila melanogaster

Alignment Length:	162	Identity:	40/162 - (24%)
Similarity:	63/162 - (38%)	Gaps:	29/162 - (17%)

- Green bases have known domain annotations that are detailed below.

Mouse    53 PPPRLPALEQGPGGLWVWGAPAV----------AQLLWPAGLGGPGGSRAAVL---VQQWVSYAD 104
            |...:|.||.  .|..:|.:.|:          :..|:|         |..||   |.|.:.:..
  Fly    52 PQHTVPLLED--NGALIWDSHAIVCYLVDKYANSDELYP---------RDLVLRAQVDQRLFFDA 105

Mouse   105 TELIPAACGATLPALGLRGPGQDPQAALGALGKALNPLEDWLRLHTYLAGDAPTLADL-AAVTAL 168
            :.|..:....::|.. ||.....|:..:..:..|...||::|..:.||.|...|:||| ...||.
  Fly   106 SILFMSLRNVSIPYF-LRQVSLVPKEKVDNIKDAYGHLENFLGDNPYLTGSQLTIADLCCGATAS 169

Mouse   169 LLPFRYVLDPSARRIWGNVTRWFNTCVRQPEF 200
            .|  ..|||....: :..|..||....:.|.:
  Fly   170 SL--AAVLDLDELK-YPKVAAWFERLSKLPHY 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vars	NP_035820.3	GST_C_family	92..213	CDD:383119	30/113 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..294
		PTZ00419	281..1263	CDD:240411
		'HIGH' region	343..353
		'KMSKS' region	861..865
GstE2	NP_611324.1	GstA	5..196	CDD:223698	39/158 (25%)
		GST_N_Delta_Epsilon	5..78	CDD:239343	7/27 (26%)
		GST_C_Delta_Epsilon	94..209	CDD:198287	28/109 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810