DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vars and GstT2

DIOPT Version :9

Sequence 1:	NP_035820.3	Gene:	Vars / 22321	MGIID:	90675	Length:	1263	Species:	Mus musculus
Sequence 2:	NP_724816.3	Gene:	GstT2 / 246386	FlyBaseID:	FBgn0050005	Length:	228	Species:	Drosophila melanogaster

Alignment Length:	166	Identity:	33/166 - (19%)
Similarity:	64/166 - (38%)	Gaps:	45/166 - (27%)

- Green bases have known domain annotations that are detailed below.

Mouse   769 EFGVSPDK---ISLQQDEDVLDTWFSSGLF---PFSIFGWPNQSEDLSV-------------FYP 814
            :|..||.:   |:|::.|.:.|.:.....|   |..:.|..:.||.:::             .||
  Fly    24 KFSNSPVEYCPIALRKFEQLTDEYKKINRFQKVPAIVGGDFHLSETIAIIRYLADKGQFDEKLYP 88

Mouse   815 GTL---------LETGHDILFFWVARMVMLGLKLTGKLPFREVYL---HAIVRDAHGRKMSKSLG 867
            .||         ||..|            |.::|...:.||:.:|   :.|.......::...:.
  Fly    89 KTLENRARVDEFLEWQH------------LNIRLACSMYFRDAWLFPMNGIAPKPKPEQIQALIE 141

Mouse   868 NVIDPLDVIHGVSLQGLYDQLLNSNLDPSEVEKAKE 903
            .|.:.|.::..:.|:.  |.|:..||..:::..:.|
  Fly   142 GVENNLGLLERLWLEN--DFLVGKNLTMADILGSSE 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vars	NP_035820.3	GST_C_family	92..213	CDD:383119
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..294
		PTZ00419	281..1263	CDD:240411	33/166 (20%)
		'HIGH' region	343..353
		'KMSKS' region	861..865		0/3 (0%)
GstT2	NP_724816.3	GST_N_Theta	5..80	CDD:239348	12/55 (22%)
		GstA	7..202	CDD:223698	33/166 (20%)
		GST_C_family	93..218	CDD:295467	17/97 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810