Protein Alignment Usp9x and Usp7

DIOPT Version :10

• Sequence 1: XP_006527649.1
• Gene: Usp9x / 22284
• MGIID: 894681
• Length: 2575
• Species: Mus musculus
• Sequence 2: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Alignment Length: 1069
• Identity: 230/1069 - (21%)
• Similarity: 376/1069 - (35%)
• Gaps: 303/1069 - (28%)

Mouse  1560 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDDVFG 1624
            |:|||||.||||||||::|.||...|:|..:..|.            .|..|:..:|........
  Fly   239 GYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIP------------TEADDSSKSVGLSLQRVF 291

Mouse  1625 YPQQFEDKPPLSKTEDRKEYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLWGEPVNLREQH 1689
            :..||.|:|            :|. :.|...||                     | |.::...||
  Fly   292 HELQFGDRP------------VGT-KKLTKSFG---------------------W-ETLDSFMQH 321

Mouse  1690 DALEFFNSLVDSLDEALKALGHPAMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQN 1754
            |..||...|:|.|:..:|.......:..:..|..:....|:...:.....|:|..:.::|::.:|
  Fly   322 DVQEFLRVLLDKLESKMKGTILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKN 386

Mouse  1755 LLDSLEQYVKGDLLEGANAYHC-----EKCNKKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECA 1814
            :.:|.:.||..:.|||.|.|..     ::.:|.|      :....||||.:.|.||.||...:.:
  Fly   387 IYESFQDYVAPETLEGDNKYDAGVHGLQEASKGV------IFTSFPPVLHLHLMRFQYDPVTDSS 445

Mouse  1815 IKFNDYFEFPRELDMEPYTVAGVAKLEGDNVNPESQLIQQNEQSESEKAGSTKYRLVGVLVHSGQ 1879
            ||:||.|||...::::.|.                        :|||.. ...|.|..||||||.
  Fly   446 IKYNDRFEFYEHINLDRYL------------------------AESENT-LADYVLHAVLVHSGD 485

Mouse  1880 ASGGHYYSYIIQRNGGDGEKNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSY 1944
            ..||||..:|..:..|     ||:||||..|:.|:   .:|...|.:||         |...:|:
  Fly   486 NHGGHYVVFINPKADG-----RWFKFDDDVVSSCR---KQEAIEQNYGG---------MDDEISF 533

Mouse  1945 RRQKRWWNAYILFYERMDTIGHDDEVIRYISEIAITT-RPHQIVMPSAIERSVRK---------- 1998
              ..:..|||:|.|.|...:   |.|:..|:|..|:: ...::.:...||.:.||
  Fly   534 --HAKCSNAYMLVYIRQSEL---DRVLGDITESEISSDLVERLDLEKRIEMARRKERGEANTYVS 593

Mouse  1999 ------QNVQFMHNRMQYSLEYFQFMKKLLTCNGVYLNPPPGQDHLSPEAEEITMISIQLAARFL 2057
                  :|.:..|.|..:.||              .::|...:...:...:|:.         .|
  Fly   594 VHVILEENFEEQHKRRLFDLE--------------KVHPRVFRIKQNQTVDELV---------DL 635

Mouse  2058 FTTGFHTKKIVRGSASDWYDALCILLRHSKNVRFWFAHNVLFNVSNRFS--EYLLE-CPSAEVRG 2119
            |..||...:                    :.:|.|   |:....:.:||  :::.| ..:.|...
  Fly   636 FVRGFGVSR--------------------QRMRMW---NLCTAQTQKFSHFDFVAEGSRTIEQIS 677

Mouse  2120 AFAKLIVFIAHFSLQDGPCPSPFASPGPSS----QAYDNLSLSDHLLRAVLNLLRREVSEHGRHL 2180
            ...|..|.....:..|.|.|.|..:|...|    :.||..:..       ||.:......|.|.|
  Fly   678 TSQKPWVIWLQLAWTDVPGPLPPFNPKTESLLFLKYYDPRNKR-------LNYIGCTQQPHTRRL 735

Mouse  2181 QQYFNLFV-MYANLGVAEKTQLLKLSVPATFMLVSLDEGPGPPIKYQYAELGKLYSVVSQLIRCC 2244
               .:|.. :.:.||....|:|......|...||:|:|    ||:      ..|:.....|....
  Fly   736 ---IDLVPDVNSKLGFEPDTELTIYDEYADKKLVNLNE----PIE------SALFIPQDHLQGHI 787

Mouse  2245 NVSSRMQSSINGNPSLPNPFGDPNLSQPIMPIQQNVVDILFVRTSYVKKIIEDCSNSDETVKLLR 2309
            .:..|  .:::....||. .||            ..:|:::    .::.|..|..|.:|
  Fly   788 LIFER--ENVDAKLDLPT-VGD------------YFLDLVY----RIEIIFSDKCNPNE------ 827

Mouse  2310 FCCWENPQFSSTVLSELLWQVAYSYTYELRPYLDLL------LQILLIEDSWQTHRIHNALKGIP 2368
                  |.|:..:.:.      |:|........:.|      ||..:..::::    ..|...:|
  Fly   828 ------PDFTLELSNR------YNYDQLANAVAERLNTDPQKLQFFMCINNYK----ETAGNAVP 876

Mouse  2369 DDRDG-LFDTIQRSKNHYQKRA-YQCIKCMVALFSSCPVAYQILQGNGDLKR--KWTWAVEWLGD 2429
            ....| :.|.:..:|....||. ||.:...:         :::     |.|:  |..|....|.|
  Fly   877 YTFKGTIKDLVSYTKQSSTKRIFYQRLSLSI---------HEL-----DNKKQFKCVWVSSDLKD 927

Mouse  2430 ELERRPYTGNPQYTYNNWSPPVQSNETSNGY---------FLERSHS----ARMTLAKACELCPE 2481
            |.|...|.              ..|:|..|.         |.|.|..    .:::..|...:|.:
  Fly   928 EKELVLYP--------------NKNDTVKGLLEEAAKKISFAENSRRKLRLLKISNHKIVAVCKD 978

Mouse  2482 EVKKATSLQEIE-------------MEESKEPDDQDAPDEHESPPPEDAPLYPHSPGSQYQQNNH 2533
            ::...|.|:..|             :||....|.|.|.:|...|....:....:|.|..:.....
  Fly   979 DIPLDTLLKSNESITTAQGAQKTFRIEEVPAEDMQLAENEFLIPVAHFSKELYNSFGIPFLTKAR 1043

Mouse  2534 VHGQPYTGPAAHHMNNPQRTGQRAQENYE 2562
             .|:|| |.....:........:..|||:
  Fly  1044 -QGEPY-GALKQRIQRRLNVQDKEWENYK 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp9x	XP_006527649.1	Ubl1_cv_Nsp3_N-like	<905..969	CDD:475130
		peptidase_C19C	1560..1963	CDD:239124	112/407 (28%)
		DUF3517	2102..2481	CDD:463438	76/409 (19%)
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	230/1069 (22%)