Protein Alignment LNX2 and Lnx2

DIOPT Version :10

• Sequence 1: NP_699202.1
• Gene: LNX2 / 222484
• HGNCID: 20421
• Length: 690
• Species: Homo sapiens
• Sequence 2: NP_542985.4
• Gene: Lnx2 / 140887
• MGIID: 2155959
• Length: 687
• Species: Mus musculus
• Alignment Length: 691
• Identity: 621/691 - (89%)
• Similarity: 647/691 - (93%)
• Gaps: 5/691 - (0%)

Human     1 MGTTSDEMVSVEQTSS-SSLNPLCFECGQQHWTRENHLYNYQNEVDDDLVCHICLQPLLQPLDTP 64
            |||||||||.|||.|| |||:|||||||||||.|||||||||.||||||||||||||||||||||
Mouse     1 MGTTSDEMVPVEQASSTSSLDPLCFECGQQHWARENHLYNYQGEVDDDLVCHICLQPLLQPLDTP 65

Human    65 CGHTFCYKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSSVCKDVMQRCDL 129
            ||||||:||||||||||||||||||||||||||||||||||||||||||||||.||:||||||||
Mouse    66 CGHTFCHKCLRNFLQEKDFCPLDRKRLHFKLCKKSSILVHKLLDKLLVLCPFSPVCQDVMQRCDL 130

Human   130 EAHLKNRCPGASHRRVALERRKTSRTQAEIENENGPTLLDPAGTLSPEADCLGTGAVPVERHLTS 194
            ||||||||||||||||.|||||||:||.:||.|.|.|::||.|||.||.||.||  ||.||:||.
Mouse   131 EAHLKNRCPGASHRRVDLERRKTSQTQTQIEGETGSTVIDPPGTLPPETDCSGT--VPGERNLTP 193

Human   195 ASLSTWSEEPGLDNPAFEESAGADTTQQPLSLPEGEITTIEIHRSNPYIQLGISIVGGNETPLIN 259
            |||..|:||||||||||||||.||:.|||||||||||||||||||||||||||||||||||||||
Mouse   194 ASLPVWTEEPGLDNPAFEESAAADSVQQPLSLPEGEITTIEIHRSNPYIQLGISIVGGNETPLIN 258

Human   260 IVIQEVYRDGVIARDGRLLAGDQILQVNNYNISNVSHNYARAVLSQPCNTLHLTVLRERRFGNRA 324
            ||||||||||||||||||||||||||||||:|||||||:|||||||||:||.||||||||||:||
Mouse   259 IVIQEVYRDGVIARDGRLLAGDQILQVNNYDISNVSHNHARAVLSQPCSTLQLTVLRERRFGSRA 323

Human   325 HNHSDSNSPREEIFQVALHKRDSGEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLSSNDRVLA 389
            ::|:|.::||:|:|||.||||||.|||||||||||||||||||||||||||||||||:|||||||
Mouse   324 NSHADGSAPRDEVFQVLLHKRDSTEQLGIKLVRRTDEPGVFILDLLEGGLAAQDGRLNSNDRVLA 388

Human   390 INGHDLKYGTPELAAQIIQASGERVNLTIARPGKPQPGNTIREAGNHSSSSQHHTPPPYYSRPSS 454
            |||||||:|||||||||||||||||||||||||||||.|..||||.||||  :|..||.:|||.|
Mouse   389 INGHDLKHGTPELAAQIIQASGERVNLTIARPGKPQPSNGSREAGAHSSS--NHAQPPSHSRPGS 451

Human   455 HKDLTQCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVL 519
            |||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   452 HKDLTRCVTCQEKHITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVL 516

Human   520 LNINGIDLTNLSHSEAVAMLKASAASPAVALKALEVQIVEEATQNAEEQPSTFSENEYDASWSPS 584
            |||||||||||||||||||||||||||||.||||||||.|||.|..|||||.|||||||||||||
Mouse   517 LNINGIDLTNLSHSEAVAMLKASAASPAVILKALEVQIAEEAAQATEEQPSAFSENEYDASWSPS 581

Human   585 WVMWLGLPSTLHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGD 649
            |||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   582 WVMWLGLPSALHSCHDIVLRRSYLGSWGFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGD 646

Human   650 MIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSLV 690
            |||||||||||||||||||||||||||||||||||||||||
Mouse   647 MIVAVNGLSTVGMSHSALVPMLKEQRNKVTLTVICWPGSLV 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LNX2	NP_699202.1	mRING-HC-C3HC3D_LNX2	45..89	CDD:319694	42/43 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..224		19/25 (76%)
		NPXY motif	208..211		2/2 (100%)
		PDZ1_LNX1_2-like	229..317	CDD:467165	83/87 (95%)
		PDZ2_LNX1_2-like	338..420	CDD:467166	77/81 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	418..455		24/36 (67%)
		PDZ3_LNX1_2-like	467..554	CDD:467167	85/86 (99%)
		PDZ4_LNX1_2-like	599..687	CDD:467168	87/87 (100%)
Lnx2	NP_542985.4	mRING-HC-C3HC3D_LNX2	46..90	CDD:319694	42/43 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..175		19/29 (66%)
		NPXY motif	207..210		2/2 (100%)
		PDZ1_LNX1_2-like	228..316	CDD:467165	83/87 (95%)
		PDZ2_LNX1_2-like	337..419	CDD:467166	77/81 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	417..454		26/38 (68%)
		PDZ3_LNX1_2-like	464..551	CDD:467167	85/86 (99%)
		PDZ4_LNX1_2-like	596..684	CDD:467168	87/87 (100%)