Protein Alignment CDHR3 and cdhr3

DIOPT Version :10

• Sequence 1: NP_689963.2
• Gene: CDHR3 / 222256
• HGNCID: 26308
• Length: 885
• Species: Homo sapiens
• Sequence 2: XP_002933155.2
• Gene: cdhr3 / 100498191
• XenbaseID: XB-GENE-6468061
• Length: 906
• Species: Xenopus tropicalis
• Alignment Length: 847
• Identity: 428/847 - (50%)
• Similarity: 555/847 - (65%)
• Gaps: 42/847 - (4%)

Human     1 MQEAIILLALLGAMS-GGEALHLILLPATGNVAENSPPGTSVHKFSVKLSASLSPVIPGFPQIVN 64
            |.:.|:|..|||.:. ||..:....||...||.||.|.||:|..|:|   .|.|.|..|||.|:|
 Frog     1 MDKLILLYFLLGVIGPGGGTVTFKGLPNLANVLENQPAGTTVFTFNV---TSTSTVNSGFPYIIN 62

Human    65 SNPLTEAFRVNWLSGTYFEVVTTGMEQLDFETGPNIFDLQIYVKDEVGVTDLQVLTVQVTDVNEP 129
            ::|:|:||.:..:..| ..||.||...|||||.||.|:|||||:|..|.||||:||:|:.:||||
 Frog    63 TSPITKAFELGVILPT-VNVVLTGNPVLDFETTPNSFNLQIYVEDSTGATDLQILTIQLINVNEP 126

Human   130 PQFQGNLA-EGLHLYIVERANPGFIYQVEAFDPEDTSRNIPLSYFLISPPKSFRMSANGTLFSTT 193
            |.|..||| :.:.:||.|....|.|||:.|.||||.|..  |.|.|......|.:|:.||:.||.
 Frog   127 PVFLDNLANQAVVIYIQEGTAAGTIYQINAIDPEDASNT--LKYSLTPTSAPFTVSSTGTVISTK 189

Human   194 ELDFEAGHRSFHLIVEVRDSGGLKASTELQVNIVNLNDEVPRFTSPTRVYTVLEELSPGTIVANI 258
            ..::|....|:.|:|:|.|..||.|:..|.|.|.|:|||.|.|...|..||:.||..|||:||.:
 Frog   190 VFNYETDPTSYSLVVQVTDPKGLSANGSLIVYITNINDETPYFIGTTSTYTIPEEQVPGTVVATV 254

Human   259 TAEDPDDEGFPSHLLYSITTVSKYFMINQLTGTIQVAQRIDRDAGELRQNPTISLEVLVKDRPYG 323
            ||.|||.:||.:.|||||.|.::||.||||||.||:|..|||||..||.:|.|:||:.|:|.|.|
 Frog   255 TAVDPDTDGFINTLLYSINTPTEYFTINQLTGVIQIAMLIDRDAVPLRLHPNITLEIKVQDSPSG 319

Human   324 GQENRIQITFIVEDVNDNPATCQKFTFSIMVPERTAKGTLLLDLNKFCFDDDSEAPNNRFNFTMP 388
            |..|...:|||:||:||||.||.::.:||.|||.....|||::|::.|.|.|.:.|||.||||..
 Frog   320 GHSNTTLLTFIIEDLNDNPPTCVQYAYSIAVPETEPLNTLLINLSQDCNDIDVQPPNNLFNFTGI 384

Human   389 SGVGSGSRFLQDPAGSGKIVLIGDLDYENPSNLAAGNKYTVIIQVQDVAPPYYKNNVYVYILTSP 453
            :|:||..||  ..:.||.|||||||::|:|:|||.||:|::.:.|||:|.|||...:|||:.|.|
 Frog   385 AGLGSNQRF--QLSSSGSIVLIGDLNFEDPNNLAVGNEYSLTVAVQDIASPYYTKYIYVYVKTIP 447

Human   454 ENEFPLIFDRPSYVFDVSERRPARTRVGQVRATDKDLPQSSLLYSISTGGASLQYPNVFWINPKT 518
            .||:|.:|:..||||:|||..|..:::|||.|||.|.|...:.|||..||::|...|:|||:..|
 Frog   448 VNEYPPVFNSSSYVFNVSELSPPGSKIGQVYATDADYPYIGITYSIVAGGSTLGATNIFWIDSNT 512

Human   519 GELQLVTKVDCETTPIYILRIQATN-NEDTSSVTVTVNILEENDEKPICTPNSYFLALPVDLKVG 582
            |.||||...|.||||.|:..:|||: ...||:.:|||||||.||:||||.||.|.||:||:..||
 Frog   513 GNLQLVNYADYETTPQYVFTVQATDPGSKTSTASVTVNILEANDDKPICLPNYYSLAVPVNQAVG 577

Human   583 TNIQNFKLTCTDLDSSPRSFRYSIGPGNVNNHFTFSPNAGSNVTRLLLTSRFDYAGGFDKIWDYK 647
            ||||||||||||.||.|.||||.|..||:||||||||:||||:|.|:|.:.||||.|.|..|:|.
 Frog   578 TNIQNFKLTCTDRDSGPTSFRYFINSGNINNHFTFSPDAGSNITSLVLANPFDYASGGDTTWNYN 642

Human   648 LLVYVTDDNLMSDRKKAEALVETGTVTLSIKVIPHPTTIITTTPRPRVTYQVLRKNVYSPSAWYV 712
            |:||:|||||:|:..:|..|::||||:|.|.|.....|..|||..|:..|.....|||:.:||||
 Frog   643 LMVYITDDNLLSNAARATGLIQTGTVSLYISVYVPGLTTHTTTTTPQNVYVTQTLNVYAATAWYV 707

Human   713 PFVITLGSILLLGLLVYLVVLLAKAIHRHCPCKTGKNKEPLTK---KGETKTAERDVVVETIQMN 774
            ||||||||:||||||.:|:.||||    :|||:  .:.:|.|:   ..|.|..:.||..|..::|
 Frog   708 PFVITLGSLLLLGLLGFLIYLLAK----YCPCR--GSPQPDTEMLIPPEPKKIKHDVFWEMTKIN 766

Human   775 TIFDGEAIDPVTGETYEFNSKTGARKWKD---PL----------------TQMPKWKESSHQGAA 820
            |:|||||.||:||..||:|||:|||:|||   |:                ||.|   ||:.:||.
 Frog   767 TVFDGEAQDPITGRIYEYNSKSGARRWKDTQQPIEPDQTLPQVAVLPGGTTQPP---ESNVKGAT 828

Human   821 PR 822
            |:
 Frog   829 PK 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDHR3	NP_689963.2	Cadherin_repeat	26..128	CDD:206637	51/101 (50%)
		Cadherin_repeat	141..231	CDD:206637	35/89 (39%)
		Cadherin_repeat	242..341	CDD:206637	56/98 (57%)
		Cadherin_repeat	465..561	CDD:206637	50/96 (52%)
		Cadherin_repeat	570..679	CDD:206637	69/108 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	808..885		6/15 (40%)
cdhr3	XP_002933155.2	Cadherin_repeat	139..227	CDD:206637	35/89 (39%)
		Cadherin_repeat	238..337	CDD:206637	56/98 (57%)
		Cadherin_repeat	346..450	CDD:206637	53/105 (50%)
		Cadherin_repeat	459..556	CDD:206637	50/96 (52%)
		Cadherin_repeat	566..664	CDD:206637	63/97 (65%)
		PTZ00449	<780..902	CDD:185628	20/54 (37%)