Protein Alignment ALDH3B2 and CG8665

DIOPT Version :10

• Sequence 1: NP_001026786.3
• Gene: ALDH3B2 / 222
• HGNCID: 411
• Length: 385
• Species: Homo sapiens
• Sequence 2: NP_610107.1
• Gene: CG8665 / 35407
• FlyBaseID: FBgn0032945
• Length: 913
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 92/342 - (26%)
• Similarity: 154/342 - (45%)
• Gaps: 36/342 - (10%)

Human    18 FIWKEPFGLVLIIAPWNYPLNLTLVLLVGALAAGSCVVLKPSEISQGTEKVLAEVL------PQY 76
            |..|||.|:..:|.||||||.:....:...:|||:..::||::....|....||:.      |..
  Fly   568 FTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGV 632

Human    77 LDQSCFAVVLGGPQETGQ-LLEHKL-DYIFFTGSPRVGKIVM-TAATKHLTPVTLELGGKNPCYV 138
            ::     |:.|...:.|| :.:|:| ..:.||||..:||.:| :.|..:|...:||||||:|..:
  Fly   633 IN-----VLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLII 692

Human   139 DDNCDPQTVANRVAWFCYFNAGQTCVAPDYVLCSPEMQERLL-PALQSTITRFYGDDPQSSPNLG 202
            ..:||............:||.|:.|:|...:.....:.:..: ..|:...|...||....|...|
  Fly   693 FADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLRTMTIGDPLDRSTAHG 757

Human   203 HIINQKQFQRL-----RALLGCSRVAIGG--QSNESDRYIAPTVLVDVQETEPVMQEEIFGPILP 260
            ...::..|.:|     |.:...:::..||  ..|....:..|||..:|.:...:.|||.||||:.
  Fly   758 PQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFIAQEESFGPIMI 822

Human   261 I--VNVQSVDEAIKFINRQEKPLALYAFSNSSQVVNQMLERTSSGSFGGNEGFTYISL-----LS 318
            |  .|...:|..::..||.|..||...|:..........:|..:|:       .::::     ::
  Fly   823 ISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGT-------VFVNVYNKTDVA 880

Human   319 VPFGGVGHSGMGRYHGK 335
            .||||...||.|:..|:
  Fly   881 APFGGFKQSGYGKDLGQ 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH3B2	NP_001026786.3	ALDH-SF	1..366	CDD:448367	92/342 (27%)
CG8665	NP_610107.1	FMT_core	5..207	CDD:444886
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	336..394	CDD:425746
		ALDH_F1L_FTFDH	428..913	CDD:143458	92/342 (27%)