DRSC/TRiP Functional Genomics Resources

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Protein Alignment FCN1 and CG9500

DIOPT Version :9

Sequence 1:NP_001994.2 Gene:FCN1 / 2219 HGNCID:3623 Length:326 Species:Homo sapiens
Sequence 2:NP_609018.3 Gene:CG9500 / 33888 FlyBaseID:FBgn0031804 Length:292 Species:Drosophila melanogaster


Alignment Length:199 Identity:83/199 - (41%)
Similarity:115/199 - (57%) Gaps:4/199 - (2%)


- Green bases have known domain annotations that are detailed below.


Human   130 GWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIH 194
            |.:|:.:...:|..|.||.:..|.||||..||....::|:|.||.||.|||...|:|::|.|.:|
  Fly    89 GIYTVQVLGLKPFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLH 153

Human   195 ALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLV-LGAFVGGSAGNSLTGHNNNFFST 258
            |:|.....||.:.|.||||..::|.|....:..|.:.|.:. ||.|. |.||:|:..:.|..|||
  Fly   154 AITKSQPHELYIHLEDFEGQTRYAHYDEIFIESENKFYAMTKLGEFT-GDAGDSMIHNRNQNFST 217

Human   259 KDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYA--NGINWSAAKGYKYSYKVSEM 321
            .|:|||....||||::.||||:.:|..|||.|:|:.|....|.  .||.|.:.:...|||||.:|
  Fly   218 FDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQM 282

Human   322 KVRP 325
            .|||
  Fly   283 MVRP 286

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FCN1NP_001994.2 Collagen 51..107 CDD:189968
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 72..111
FReD 115..325 CDD:238040 81/197 (41%)
A domain, contributes to trimerization 115..154 7/23 (30%)
B domain, contributes to trimerization 155..243 35/88 (40%)
Carbohydrate-binding. /evidence=ECO:0000269|PubMed:17897951 282..284 0/1 (0%)
P domain. /evidence=ECO:0000303|PubMed:17148457 317..326 6/9 (67%)
CG9500NP_609018.3 FReD 76..287 CDD:238040 83/199 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 186 1.000 Domainoid score I3350
eggNOG 1 0.900 - - E1_KOG2579
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 188 1.000 Inparanoid score I3915
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000029
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X25
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
76.860

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