Protein Alignment RBM24 and sup-12

DIOPT Version :9

• Sequence 1: NP_001137414.1
• Gene: RBM24 / 221662
• HGNCID: 21539
• Length: 236
• Species: Homo sapiens
• Sequence 2: NP_508674.1
• Gene: sup-12 / 180674
• WormBaseID: WBGene00006321
• Length: 248
• Species: Caenorhabditis elegans
• Alignment Length: 246
• Identity: 120/246 - (48%)
• Similarity: 135/246 - (54%)
• Gaps: 43/246 - (17%)

Human     6 KDTTYTKIFVGGLPYHTTDASLRKYFEVFGEIEEAVVITDRQTGKSRGYGFVTMADRAAAERACK 70
            :||.:||||||||||||:|.:|.:|||.||:||||||||||.|.||||||||||.|||:||||||
 Worm    30 RDTMFTKIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKSRGYGFVTMKDRASAERACK 94

Human    71 DPNPIIDGRKANVNLAYLGAKPR--IMQPGFAFGVQQLH-----PALIQRPFGIPAHYVYPQAFV 128
            |||||||||||||||||||||||  :.....|.|..||.     .||.|...|:|..| ||..
 Worm    95 DPNPIIDGRKANVNLAYLGAKPRTNVQLAALAAGQVQLPLTTQLQALFQPRMGLPQMY-YPTV-- 156

Human   129 QPGVVIPHVQPTAAAASTTPYIDYTGAAYAQYSAAAAA---------AAAAAAYDQYPYAASPAA 184
             .|:|.|.:....|||....: ||...|......||||         |||....:|  |||.||
 Worm   157 -TGLVNPLMAQQGAAAQQQLF-DYNALAAVMNPQAAAAYGIQSQGKFAAAPTTIEQ--YAAYPA- 216

Human   185 AGYVTAGGYGYAVQQPITAAAPGTAAAAAAAAAAAAAFGQYQPQQLQTDRM 235
                   |||...|.......|.....|||            .|||:..|:
 Worm   217 -------GYGLVPQSAYNIGNPQLQQLAAA------------QQQLEHQRV 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBM24	NP_001137414.1	RRM_RBM24_RBM38_like	11..86	CDD:409818	63/74 (85%)
		Necessary for interaction with EIF4E. /evidence=ECO:0000269|PubMed:29358667	175..199		9/23 (39%)
sup-12	NP_508674.1	RRM_RBM24_RBM38_like	35..110	CDD:240830	63/74 (85%)
		ELAV_HUD_SF	<37..>209	CDD:273741	98/176 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4731
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I3085
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1579773at2759
OrthoFinder	1	1.000	-	-		FOG0001012
OrthoInspector	1	1.000	-	-		otm16559
orthoMCL	1	0.900	-	-		OOG6_105204
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1267
SonicParanoid	1	1.000	-	-		X602
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.900