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Protein Alignment Tubb2a and gammaTub23C

DIOPT Version :10

Sequence 1:	NP_033476.1	Gene:	Tubb2a / 22151	MGIID:	107861	Length:	445	Species:	Mus musculus
Sequence 2:	NP_476804.1	Gene:	gammaTub23C / 33501	FlyBaseID:	FBgn0260639	Length:	475	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	156/457 - (34%)
Similarity:	268/457 - (58%)	Gaps:	22/457 - (4%)

- Green bases have known domain annotations that are detailed below.

Mouse     3 EIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVD 67
            ||:.:|.||||||||.:||:.:..||||.|:|.....::..|:|.:|::.:|..:.|:|||:|:|
  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVLEDFANDGLDRKDVFFYQADDDHYIPRAVLLD 68

Mouse    68 LEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCL 130
            |||..::::....:.:::.|:|....:  .|||||||.| |::|.:|.:.|.|::.:|::..|.|
  Fly    69 LEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSDSL 132

Mouse   131 QGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPS-PKVSDTVVEPYNATLSVHQLVE 194
            :||.|.||:.||||||||:.::.::.:.||.:::.||||.|: .::||.||:|||:.|::.:|..
  Fly   133 EGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRLTT 197

Mouse   195 NTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 259
            ..|....:||.||..|....|.:..|::..:|:|||..||..||.||:|..:|.:|..|...::|
  Fly   198 AADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPLIP 262

Mouse   260 FPRLHFFMPGFAPLTSRG---SQQ---YRALTVPELTQQMFDSKNMMAACDP---RHGRYLTVAA 315
            .|:|||.|.|:.||||..   :||   .|..||.::.:::...||||.:..|   .|..|:::..
  Fly   263 TPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISILN 327

Mouse   316 IFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPP---RGLKMSATFIGNSTAIQEL 377
            |.:|.:...:|.:.:..::::..:.|:.|.|.:::.|:....|   ...::|...:.|.|:|..|
  Fly   328 IIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGLMLANHTSICSL 392

Mouse   378 FKRISEQFTAMFRRKAFLHWYTGEGM---DEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEE 439
            |:|...|:..:.:|.|||..:..|.:   |..|..|:...::.||   |:|:.||.::..:|..:
  Fly   393 FERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLV---QEYEAATREDYMQFSVK 454

Mouse   440 EG 441
            .|
  Fly   455 RG 456

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.