Protein Alignment FCGR2A and Fcgr2b

DIOPT Version :9

• Sequence 1: XP_011507589.1
• Gene: FCGR2A / 2212
• HGNCID: 3616
• Length: 369
• Species: Homo sapiens
• Sequence 2: XP_006250295.1
• Gene: Fcgr2b / 289211
• RGDID: 631331
• Length: 342
• Species: Rattus norvegicus
• Alignment Length: 291
• Identity: 141/291 - (48%)
• Similarity: 184/291 - (63%)
• Gaps: 14/291 - (4%)

Human    10 NVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQ 74
            :|..|.|:.:...|.:|.|. |:|.|.. ||||:|||||||.||:||:|||.|:|..:.::.|.|
  Rat    19 HVLSRTLYHMLLWTAVLNLV-AESHAGL-PKAVVKLEPPWIQVLKEDTVTLMCEGTHNTKNCSTQ 81

Human    75 WFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETI 139
            |||||:.|....|.:|.|||..||||||.|:..:|.:|:|:||.|:|:||:|||..|.|:|||||
  Rat    82 WFHNGSSIWHQAQANYTFKATVNDSGEYRCRMEETGISEPIHLGVISDWLLLQTSQLVFEEGETI 146

Human   140 MLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVTIT 204
            .|||||||:|.|.||..|||||..::.|....||||:|||||||:|:|...:|.|:..|||||||
  Rat   147 TLRCHSWKNKQLTKVLLFQNGKPVRYYHQSSNFSIPKANHSHSGNYYCKAYLGRTMHVSKPVTIT 211

Human   205 VQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAI 269
            ||.|...||.|:..|||.|...||||||..:|:|:|.:||:        |.|....|..|:|
  Rat   212 VQEPKSSSSLPVLTIVAAVAGIAVAAIVIILVSLVYLKKKQ--------VPALPGNPDHREM--- 265

Human   270 RKRQLEETNNDYETADGGYMTLNPRAPTDDD 300
             ...|.|...:|....||.:.::|..|:..|
  Rat   266 -GEALPEELGEYRKPSGGSVPVSPGPPSGLD 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FCGR2A	XP_011507589.1	Ig1_FcgammaR_like	41..119	CDD:143229	43/77 (56%)
		IG_like	47..119	CDD:214653	38/71 (54%)
		Ig2_FcgammaR_like	123..205	CDD:143230	50/81 (62%)
		IG_like	129..205	CDD:214653	45/75 (60%)
Fcgr2b	XP_006250295.1	Ig	48..126	CDD:299845	43/77 (56%)
		IG_like	54..112	CDD:214653	32/57 (56%)
		Ig2_FcgammaR_like	130..212	CDD:143230	50/81 (62%)
		IG_like	136..212	CDD:214653	45/75 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83678856
Domainoid	1	1.000	112	1.000	Domainoid score	I40068
eggNOG	1	0.900	-	-		E1_2ESZP
HGNC	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I14652
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG34347
OrthoDB	1	1.010	-	-		D1246375at2759
OrthoFinder	1	1.000	-	-		FOG0001730
OrthoInspector	1	1.000	-	-		mtm10029
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11481
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X79
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870