Protein Alignment FCGR2A and Fcgr2b

DIOPT Version :9

• Sequence 1: XP_011507589.1
• Gene: FCGR2A / 2212
• HGNCID: 3616
• Length: 369
• Species: Homo sapiens
• Sequence 2: NP_001070657.1
• Gene: Fcgr2b / 14130
• MGIID: 95499
• Length: 340
• Species: Mus musculus
• Alignment Length: 290
• Identity: 146/290 - (50%)
• Similarity: 183/290 - (63%)
• Gaps: 20/290 - (6%)

Human     8 SQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDS 72
            |:.:|...||     |.:|.||:.....   ||||:|||||||.||:||:|||||:|..:|.:.|
Mouse    21 SRTLCHMLLW-----TAVLNLAAGTHDL---PKAVVKLEPPWIQVLKEDTVTLTCEGTHNPGNSS 77

Human    73 IQWFHNGNLIPTHTQPSYRFKANNNDSGEYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGE 137
            .||||||..|.:..|.||.|||..||||||.||..||.|||||.|.|:|:||:||||.|.|.|||
Mouse    78 TQWFHNGRSIRSQVQASYTFKATVNDSGEYRCQMEQTRLSDPVDLGVISDWLLLQTPQLVFLEGE 142

Human   138 TIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPVT 202
            ||.||||||::|.|.:::||.|.||.::.|....||||:|||||||||:|.|::|.||..|||||
Mouse   143 TITLRCHSWRNKLLNRISFFHNEKSVRYHHYSSNFSIPKANHSHSGDYYCKGSLGRTLHQSKPVT 207

Human   203 ITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMI 267
            ||||.|....|.|:..|||.|...||||||..:|:|:|.:||:        |.|....|..|:|
Mouse   208 ITVQGPKSSRSLPVLTIVAAVTGIAVAAIVIILVSLVYLKKKQ--------VPALPGNPDHREM- 263

Human   268 AIRKRQLEETNNDYETADGGYMTLNPRAPT 297
               ...|.|...:|....||.:.::|..|:
Mouse   264 ---GETLPEEVGEYRQPSGGSVPVSPGPPS 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FCGR2A	XP_011507589.1	Ig1_FcgammaR_like	41..119	CDD:143229	50/77 (65%)
		IG_like	47..119	CDD:214653	45/71 (63%)
		Ig2_FcgammaR_like	123..205	CDD:143230	51/81 (63%)
		IG_like	129..205	CDD:214653	46/75 (61%)
Fcgr2b	NP_001070657.1	Ig	46..124	CDD:299845	50/77 (65%)
		IG_like	52..110	CDD:214653	35/57 (61%)
		Ig2_FcgammaR_like	128..210	CDD:143230	51/81 (63%)
		IG_like	134..210	CDD:214653	46/75 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83953381
Domainoid	1	1.000	113	1.000	Domainoid score	I42125
eggNOG	1	0.900	-	-		E1_2ESZP
HGNC	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	341	1.000	Inparanoid score	I14570
Isobase	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG34347
OrthoDB	1	1.010	-	-		D1246375at2759
OrthoFinder	1	1.000	-	-		FOG0001730
OrthoInspector	1	1.000	-	-		mtm9907
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11481
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X79
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.870