Protein Alignment SLC16A9 and CG8468

DIOPT Version :10

• Sequence 1: XP_016871372.1
• Gene: SLC16A9 / 220963
• HGNCID: 23520
• Length: 551
• Species: Homo sapiens
• Sequence 2: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Alignment Length: 681
• Identity: 166/681 - (24%)
• Similarity: 258/681 - (37%)
• Gaps: 195/681 - (28%)

Human     7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSL 71
            ||.||.||::..|||...:..|.....|::..:.:..||..|...|:|.||.||..|:|.|..|.
  Fly    44 PDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVSA 108

Human    72 CVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDDRR 136
            ..:.||.|||||......|....||.||.::.:||..||::.|:|..::|...|.|...||:..|
  Fly   109 MANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWR 173

Human   137 GLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRPLQ--------- 192
            .||.|:...||.||.|::|.|.::|:: .|....|.|.|.:.|:....|...||:|
  Fly   174 ALATGVAMCGSGVGTFVFAPLTKILLK-SGWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTNE 237

Human   193 SSDCPLPKK-------IAP----------EDLPD---KYSIYNE--------------------- 216
            ..|....||       :||          :.||:   .||:.|.
  Fly   238 EGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIF 302

Human   217 KGKNLEENINILDKSYSSEE-----KCRITLANGDWKQDSL-LHKNPTVT--------------- 260
            ||.|||...:...:.....|     |.:.|..|||.:|.:. |||..|..
  Fly   303 KGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLET 367

Human   261 -----------HT---KEPETYKKKVA--------------------EQTYFCKQLAK------- 284
                       ||   :.|:...|:.|                    :..:|...|.:
  Fly   368 EAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQ 432

Human   285 -------------RKWQLYKN------YCGETV----------ALFKNKVFSALFIAILLFDIGG 320
                         .|..:.::      .|.|.|          .|.|:..|..|..:..|..:|.
  Fly   433 TSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGF 497

Human   321 FPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLA 385
            |.|...:.|.|:::.: :|:....::|.||::....:::.|.|:.|..:..|:|....|...|:|
  Fly   498 FVPFTFLVDRAKAAGM-DEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIA 561

Human   386 -LCA---IPFAKSYVTLALLSGI-LGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSL 445
             :|:   |..|..: |.||..|| :...:...|:   :..:.:|:|||.:|||.||.|.||..:.
  Fly   562 TICSGIVINTATQW-TFALFFGICIACFSALRSL---IAVELIGLEKLTNAYGFLMLFQGLAATF 622

Human   446 GPPIVGKIFILKSSHFTVLPCHISRYRGPDCNSSTDLYKRNLHGTSHGWFYDWTQTYDIAFYFSG 510
            |.||.|.::::                                          |.:|:.||||:|
  Fly   623 GSPIAGGLYVM------------------------------------------TGSYNAAFYFAG 645

Human   511 FCVLLGGFILL-LAALPSWDTCNKQLPKPAP 540
            ..:||..|:.. |..:..|:....:...|.|
  Fly   646 GLILLSAFLCYPLTWVSRWEERRNEKLTPLP 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A9	XP_016871372.1	MFS_MCT9	12..524	CDD:340986	159/658 (24%)
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	61/176 (35%)
		MFS	<477..658	CDD:475125	57/227 (25%)