Protein Alignment SLC16A9 and CG8034

DIOPT Version :10

• Sequence 1: XP_016871372.1
• Gene: SLC16A9 / 220963
• HGNCID: 23520
• Length: 551
• Species: Homo sapiens
• Sequence 2: NP_573376.2
• Gene: CG8034 / 32924
• FlyBaseID: FBgn0031011
• Length: 647
• Species: Drosophila melanogaster
• Alignment Length: 648
• Identity: 128/648 - (19%)
• Similarity: 225/648 - (34%)
• Gaps: 190/648 - (29%)

Human     4 KKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASPV 68
            |.:||||||||..|...|..........:.|:|:.:.|        |...||:..:.|.:.|..|
  Fly     8 KVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTL--------KELNVGTTGAAVIISALDV 64

Human    69 C--------SLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATV 125
            |        ...:..|..|.|.|....:...||.|:|.|.::..:..:|.::.|:|.||..:|..
  Fly    65 CMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAF 129

Human   126 TITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRP 190
            .....||..:||.|:||...|:::|:.|...|.|:|:|.|...|.:|::..:|||......|::|
  Fly   130 VALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQP 194

Human   191 LQ--------------SSDCPLPK-------------------KIAPED------LPDKYSIYNE 216
            ::              .|..|.|:                   |:..||      ||:..::...
  Fly   195 VKWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFH 259

Human   217 K--------GKNLEE-NINILDKS--------------------------------YSSEE---- 236
            |        .||..| .:|.::.|                                |:|:.
  Fly   260 KPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNA 324

Human   237 ---KCR-------------------ITLANGD---WKQDSLLHKNPTVTHT-----------KEP 265
               :||                   :.|..||   .:.|..|.:..|.|.:           |..
  Fly   325 TQLRCRKASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMK 389

Human   266 ETYKKKVAEQTYFCKQLAKRK------WQLYKNYCGETVALFKNKVFSALFIAILLFDIGGFPPS 324
            .|...|.||......:.||:|      |:.:.:..  .:.:.|:|:|..|...:.:|.:......
  Fly   390 PTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLL--DIDMLKDKMFLNLLFGLSIFYVAEMNFK 452

Human   325 LLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAI 389
            ::......:...::.: :...:||..|.....:::|..:.|...|....:::.::|.:.|....:
  Fly   453 MVTPFFFANLGYQKTD-VAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSIIFVALTRSIM 516

Human   390 PFAKSYVTLALLSGILGFLTGN-WSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGK- 452
            .....:..|.:...|.||..|: .|.|....::...:|||..|:|.             .:|||
  Fly   517 AEQTEWTQLMIWLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGW-------------HLVGKA 568

Human   453 IFILKSSHFTVLPCHISRYRGPDCNSSTDLYKRNLHGTSHGWFYDWTQTYDIAFYFSGFCVLL 515
            :|::                              ..|...|...|.|.:|.|..:....|:::
  Fly   569 LFVI------------------------------TFGPLIGLIRDVTDSYPICIHTQSVCIMI 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A9	XP_016871372.1	MFS_MCT9	12..524	CDD:340986	122/640 (19%)
CG8034	NP_573376.2	MFS	16..>193	CDD:475125	51/184 (28%)
		MFS	<428..609	CDD:475125	36/218 (17%)