DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FCER1A and CG7166

DIOPT Version :9

Sequence 1:	NP_001374209.1	Gene:	FCER1A / 2205	HGNCID:	3609	Length:	257	Species:	Homo sapiens
Sequence 2:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	193	Identity:	42/193 - (21%)
Similarity:	63/193 - (32%)	Gaps:	65/193 - (33%)

- Green bases have known domain annotations that are detailed below.

Human    20 PDGVLAVPQKPKVSLNPPWNRIFKGENVTLTC--NGNNFFEVSSTKWFHNGSLSEET----NSSL 78
            |..:.|:|...:|:..       ||..|||.|  :||   .|.:..||.....|..|    :|:|
  Fly   134 PPTLRALPHNGQVTAR-------KGSTVTLECKASGN---PVPTIFWFKKDVFSGPTHLSDSSTL 188

Human    79 NIVNAKFEDSGEYKCQHQ-----------QVNESEPVYLEVFSDWLLLQASAEVVMEGQPLFLRC 132
            .:.|.....:|.|:|...           |:....|..:.|...|:
  Fly   189 ILENVDRHHAGTYQCSADNGVKDRVSMDIQLTILSPPEITVEKSWV------------------- 234

Human   133 HGWRNWDVYKV-IYYKDGEALKYWYEN------------------HNISITNATVEDSGTYYC 176
            |....:||..| |.:.|..:...||:|                  :::.|.|....|.|.|.|
  Fly   235 HASEGYDVELVCIVHGDVNSEMLWYQNSFLLDATDRRSMYPRDDRYSLIIRNFQPTDFGNYSC 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FCER1A	NP_001374209.1	Ig1_FcgammaR_like	30..108	CDD:409410	22/94 (23%)
		Ig strand B	47..51	CDD:409410	3/3 (100%)
		Ig strand C	61..65	CDD:409410	0/3 (0%)
		Ig strand E	76..80	CDD:409410	2/3 (67%)
		Ig strand F	90..95	CDD:409410	2/4 (50%)
		Ig strand G	101..104	CDD:409410	0/2 (0%)
		Ig2_FcgammaR_like	112..194	CDD:409411	16/84 (19%)
		Ig strand B	128..132	CDD:409411	0/3 (0%)
		Ig strand C	142..146	CDD:409411	2/4 (50%)
		Ig strand E	159..163	CDD:409411	0/3 (0%)
		Ig strand F	173..178	CDD:409411	2/4 (50%)
		Ig strand G	187..190	CDD:409411
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653
		Ig	56..116	CDD:143165
		IG_like	144..221	CDD:214653	21/86 (24%)
		IGc2	151..209	CDD:197706	18/60 (30%)
		IG_like	232..313	CDD:214653	16/85 (19%)
		Ig	242..311	CDD:143165	13/56 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910