Protein Alignment Tpst1 and Tpst

DIOPT Version :10

• Sequence 1: NP_038865.1
• Gene: Tpst1 / 22021
• MGIID: 1298231
• Length: 370
• Species: Mus musculus
• Sequence 2: NP_001259518.1
• Gene: Tpst / 32312
• FlyBaseID: FBgn0086674
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 336
• Identity: 204/336 - (60%)
• Similarity: 260/336 - (77%)
• Gaps: 3/336 - (0%)

Mouse    14 LVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVP 78
            :::.::.:|...:....|..:::..::   |.:....|...|.....:.::|:::||||||||||
  Fly    18 IIVITMFLFKFTELRPTCLFKVDAANE---LSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVP 79

Mouse    79 RSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLL 143
            ||||||||||||||||:|||:|||||||||.|:..|.:|.||.:||.|||:|.||::||:..|.|
  Fly    80 RSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCL 144

Mouse   144 EVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSY 208
            |:|.|||||||.||||||..||..:|:..||||||||.|||||||:|||:|||||||.||||:||
  Fly   145 EIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSY 209

Mouse   209 RDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIG 273
            |.|:.|||.|||.|:.||.::|..:||:|:|||||||||.|||.:||||.:|||.:||||||.|.
  Fly   210 RQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFIN 274

Mouse   274 KAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKP 338
            |..||.|||||||:||||||||:.|:|||||:||.||::|||.|||||:.||||||||||:||||
  Fly   275 KPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKP 339

Mouse   339 DPKILENTRRV 349
            |..:.:||.::
  Fly   340 DAWVQDNTSKL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpst1	NP_038865.1	Sulfotransfer_3	72..261	CDD:463887	132/188 (70%)
		Interaction with peptide substrate. /evidence=ECO:0000250|UniProtKB:O60507	102..106		3/3 (100%)
Tpst	NP_001259518.1	Sulfotransfer_3	73..264	CDD:463887	134/190 (71%)