Protein Alignment Tpst1 and Tpst

DIOPT Version :9

• Sequence 1: NP_001123948.1
• Gene: Tpst1 / 22021
• MGIID: 1298231
• Length: 370
• Species: Mus musculus
• Sequence 2: NP_001259518.1
• Gene: Tpst / 32312
• FlyBaseID: FBgn0086674
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 336
• Identity: 204/336 - (60%)
• Similarity: 260/336 - (77%)
• Gaps: 3/336 - (0%)

Mouse    14 LVISSVTVFYLGQHAMECHHRIEERSQPARLENPKATVRAGLDIKANKTFTYHKDMPLIFIGGVP 78
            :::.::.:|...:....|..:::..::   |.:....|...|.....:.::|:::||||||||||
  Fly    18 IIVITMFLFKFTELRPTCLFKVDAANE---LSSQMVRVEKYLTDDNQRVYSYNREMPLIFIGGVP 79

Mouse    79 RSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQMWSRSSKEKIRLDEAGVTDEVLDSAMQAFLL 143
            ||||||||||||||||:|||:|||||||||.|:..|.:|.||.:||.|||:|.||::||:..|.|
  Fly    80 RSGTTLMRAMLDAHPDVRCGQETRVIPRILQLRSHWLKSEKESLRLQEAGITKEVMNSAIAQFCL 144

Mouse   144 EVIVKHGEPAPYLCNKDPFALKSLTYLARLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSY 208
            |:|.|||||||.||||||..||..:|:..||||||||.|||||||:|||:|||||||.||||:||
  Fly   145 EIIAKHGEPAPRLCNKDPLTLKMGSYVIELFPNAKFLFMVRDGRATVHSIISRKVTITGFDLSSY 209

Mouse   209 RDCLTKWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLHIPWNHSVLHHEEMIG 273
            |.|:.|||.|||.|:.||.::|..:||:|:|||||||||.|||.:||||.:|||.:||||||.|.
  Fly   210 RQCMQKWNHAIEVMHEQCRDIGKDRCMMVYYEQLVLHPEEWMRKILKFLDVPWNDAVLHHEEFIN 274

Mouse   274 KAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQDMAVIAPMLAKLGYDPYANPPNYGKP 338
            |..||.|||||||:||||||||:.|:|||||:||.||::|||.|||||:.||||||||||:||||
  Fly   275 KPNGVPLSKVERSSDQVIKPVNLEAMSKWVGQIPGDVVRDMADIAPMLSVLGYDPYANPPDYGKP 339

Mouse   339 DPKILENTRRV 349
            |..:.:||.::
  Fly   340 DAWVQDNTSKL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpst1	NP_001123948.1	Sulfotransfer_3	72..261	CDD:404368	132/188 (70%)
		PAPS binding. /evidence=ECO:0000250|UniProtKB:O60507	79..83		3/3 (100%)
		Interaction with peptide substrate. /evidence=ECO:0000250|UniProtKB:O60507	102..106		3/3 (100%)
		PAPS binding. /evidence=ECO:0000250|UniProtKB:O60507	286..295		7/8 (88%)
Tpst	NP_001259518.1	Sulfotransfer_3	70..258	CDD:290204	133/187 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834605
Domainoid	1	1.000	300	1.000	Domainoid score	I1419
eggNOG	1	0.900	-	-		E2759_KOG3988
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2667
Inparanoid	1	1.050	433	1.000	Inparanoid score	I1695
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003498
OrthoInspector	1	1.000	-	-		otm43406
orthoMCL	1	0.900	-	-		OOG6_104250
Panther	1	1.100	-	-	O	PTHR12788
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2858
SonicParanoid	1	1.000	-	-		X2392
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.780