Protein Alignment SLC37A2 and spin

DIOPT Version :10

• Sequence 1: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_524823.1
• Gene: spin / 45380
• FlyBaseID: FBgn0086676
• Length: 630
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 95/470 - (20%)
• Similarity: 171/470 - (36%)
• Gaps: 125/470 - (26%)

Human    17 RDSWFRGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKD 81
            |..||...:|....||   .:|.|..|:.|              :.|..  ||        ||..
  Fly   111 RSQWFTVTVLCFVNLI---NYMDRFTIAGV--------------LTDVR--ND--------FDIG 148

Human    82 NYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIHELWYF 146
            |  :..|.:...|:|:|.:...|.|..|:|....:.::.|:   ||:::...||.|  :.:..:|
  Fly   149 N--DSAGLLQTVFVISYMVCAPIFGYLGDRYSRPWIMAVGV---GLWSTTTLLGSF--MKQFGWF 206

Human   147 VVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGN----ILGSLIAGIWVNGQW 207
            :..:...|:.:.:......|.:.:.|....|..::.::.....||:    |:||..|.:..:.:|
  Fly   207 IAFRALVGIGEASYSTIAPTIISDLFVHDMRSKMLALFYFAIPVGSGLGYIVGSKTAHLANDWRW 271

Human   208 GLSFIVPGIITAVMGVITFLFLIEHPEDVDCAPPQHHGEPAEN-------QDNPEDPGNSPCSIR 265
            .|.      :|.::|::. :|||...:|    |.:.|.|.:.|       ||......|....:.
  Fly   272 ALR------VTPILGIVA-VFLILLIKD----PVRGHSEGSHNLEATTYKQDIKALVRNRSFMLS 325

Human   266 ESGLETVAKCSK-----GPCEEPAAISFFGALRIPG---VVEFSLCLLFAKLVSYTFLYWLPLYI 322
            .:|...||..:.     ||     :..:.|....||   :|:..:...|..:.....|..:||
  Fly   326 TAGFTCVAFVAGALAWWGP-----SFIYLGMKMQPGNENIVQDDVAFNFGVITMLAGLLGVPL-- 383

Human   323 ANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYNYIGQDGI 387
                       |...:.:            ||..|.......|...|:::||::
  Fly   384 -----------GSFLSQY------------LVKRYPTADPVICAFGLLVSAPLL----------- 414

Human   388 ASSIVMLIICGGLVNGPYALI---------TTAVSADLGTH---KSLKGNAKALSTVTAIIDGTG 440
             :...:|:....:  |.||||         ..|:.||:..:   .:.:..|:|...:.     :.
  Fly   415 -TGACLLVNSNSV--GTYALIFFGQLALNLNWAIVADILLYVVVPTRRSTAEAFQILI-----SH 471

Human   441 SIGAALGPLLAGLIS 455
            ::|.|..|.|.|.||
  Fly   472 ALGDAGSPYLVGAIS 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC37A2	NP_938018.1	MFS_SLC37A1_2	22..484	CDD:340902	92/465 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		7/28 (25%)
spin	NP_524823.1	MFS_spinster_like	117..571	CDD:340886	92/464 (20%)