Protein Alignment SLC37A2 and MFS16

DIOPT Version :10

• Sequence 1: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_726048.1
• Gene: MFS16 / 37427
• FlyBaseID: FBgn0034611
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 496
• Identity: 261/496 - (52%)
• Similarity: 324/496 - (65%)
• Gaps: 31/496 - (6%)

Human    17 RDSWFRGLILLLTFLIYACYHMSRKPISIVKSRLHQNCSEQIKPINDTHSLNDTMWCSWAPFDKD 81
            ||..::..:.:||||.||||||.|||||:|||.|..|||..:......        |.:||||..
  Fly    80 RDLLYKMSVFVLTFLAYACYHMCRKPISVVKSVLQGNCSTALAASGQD--------CGYAPFDVP 136

Human    82 NYKELLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYFWNIHELWYF 146
            :...|.|.:|:|||.:|||.||.||...||:.|||:||.||:|:|:||.:||:....|||.||||
  Fly   137 DATTLFGMLDSAFLFSYAIAMFASGFVAERVSLRYFLSMGMILTGVFTYMFGIARTSNIHSLWYF 201

Human   147 VVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGIWVNGQWGLSF 211
            :::|:..|:.||||||.||..||.||||.|||.|.||||||||:|||||:|||..:|...|.|||
  Fly   202 IIVQIFAGIFQTTGWPGVVALVGRWFGKSKRGLIFGIWNSHTSIGNILGTLIAAHYVESDWALSF 266

Human   212 IVPGIITAVMGVITFLFLIEHPEDVDCAPP--QHHGEPAENQDNPEDPGNSPCSIRESGLETVAK 274
            :|||||.|.:|.:.||||::.||.|.|.|.  ||....|...|..:|...   .:|.:..|...:
  Fly   267 VVPGIIIAAVGFLLFLFLVDQPEIVGCYPQAGQHERRVANESDVEQDDEE---QVRHNDAEINYR 328

Human   275 CSKG------PCEEPAA--------ISFFGALRIPGVVEFSLCLLFAKLVSYTFLYWLPLYIANV 325
            .:..      |..:|.|        ||...||.|||||||||||.|.|||||||:|||||||...
  Fly   329 SAPTERTPILPRSQPEAVPRGRGRPISLIDALFIPGVVEFSLCLFFTKLVSYTFMYWLPLYIQKS 393

Human   326 AHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATTCCVMLILAAPMMFLYNYIGQDGIASS 390
            :....:.:.|||||||||||:|.|.||.:||.:...||.|..||.:|:|::.:|...|...:..|
  Fly   394 STLGPELSADLSTLFDVGGILGAIAAGYLSDVSGMSATVCTGMLFVASPILLMYQQYGALSMTIS 458

Human   391 IVMLIICGGLVNGPYALITTAVSADLGTHKSLKGNAKALSTVTAIIDGTGSIGAALGPLLAGLIS 455
            ||:||:.|..||||||||||:|||:||.|.||:|||.||:|||||||||||||||:|||||||||
  Fly   459 IVLLIVVGIFVNGPYALITTSVSAELGQHSSLEGNANALATVTAIIDGTGSIGAAVGPLLAGLIS 523

Human   456 PTGWNNVFYMLISADVLACLLLCRLVYKEILAWKVSLSRGS 496
            ..||..||:|||:||::|.:||.|||:||..|    |.|.|
  Fly   524 TAGWQYVFHMLIAADIIAMVLLGRLVFKEFAA----LRRAS 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC37A2	NP_938018.1	MFS_SLC37A1_2	22..484	CDD:340902	253/477 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		6/23 (26%)
MFS16	NP_726048.1	MFS_SLC37A1_2	85..552	CDD:340902	253/477 (53%)