Protein Alignment TYSND1 and HtrA2

DIOPT Version :10

• Sequence 1: NP_775826.2
• Gene: TYSND1 / 219743
• HGNCID: 28531
• Length: 566
• Species: Homo sapiens
• Sequence 2: NP_650366.1
• Gene: HtrA2 / 41756
• FlyBaseID: FBgn0038233
• Length: 422
• Species: Drosophila melanogaster
• Alignment Length: 200
• Identity: 49/200 - (24%)
• Similarity: 80/200 - (40%)
• Gaps: 48/200 - (24%)

Human   357 GSGVAVAPR-LVVTCRHV---SPREAARVLVRSTTPKSVAIWGRVVFATQETCPYDIAVVSLEED 417
            |||..:... |::|..||   .|....:|.:..         ||       |.|..|..|....|
  Fly   141 GSGFIIEQNGLILTNAHVVINKPHTMVQVRLSD---------GR-------TFPATIEDVDQTSD 189

Human   418 LDDVPIPV---------PAEHFHEGEAVSVVGFGVFGQSCGPSVTSGILSAVVQV-------NGT 466
            |..:.|.|         .:.....||.|..:|..:   :...:||:|::|:..:.       |..
  Fly   190 LATLRIQVNNLSVMRLGKSSTLRSGEWVVALGSPL---ALSNTVTAGVISSTQRASQELGLRNRD 251

Human   467 PVMLQTTCAVHSGSSGGPLFSNHSGNLLGIITSNTRDNNTGATYPHLNFSIPITVLQPALQQYSQ 531
            ...|||..|:..|:|||||. |..|..:|:   |:.....|     ::|:|||..::..|::.::
  Fly   252 INYLQTDAAITFGNSGGPLV-NLDGEAIGV---NSMKVTAG-----ISFAIPIDYVKVFLERAAE 307

Human   532 TQDLG 536
            .:..|
  Fly   308 KRKKG 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TYSND1	NP_775826.2	Trypsin_2	357..496	CDD:433149	40/158 (25%)
HtrA2	NP_650366.1	DegQ	141..421	CDD:440035	48/199 (24%)