Protein Alignment TYSND1 and CG3589

DIOPT Version :10

• Sequence 1: NP_775826.2
• Gene: TYSND1 / 219743
• HGNCID: 28531
• Length: 566
• Species: Homo sapiens
• Sequence 2: NP_611968.1
• Gene: CG3589 / 37966
• FlyBaseID: FBgn0035065
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 491
• Identity: 130/491 - (26%)
• Similarity: 201/491 - (40%)
• Gaps: 111/491 - (22%)

Human   118 PAPSRGRPL------QPRLPAELLLLLSCPAFWAHFARLF-GDEAAEQWRFSSAARDDEVSEDEE 175
            |...|.||:      ||.:.:.         |.||...:| .:|............|    ..:.
  Fly    88 PQQRRPRPIAAPGSRQPHILSR---------FTAHPLYVFCANEVCRNLHHILLTAD----SGDA 139

Human   176 ADQLRALGWFALLGVRLGQEEVEEERGPA------MAVSPLGAVPKGAPLLVCGSPFGAFCPDIF 234
            .:.||:.  |.:||:|..::|...:|..|      ..:.|:..:.   .:||..||||.   :.|
  Fly   140 GEVLRSS--FVVLGLRKPEKEKSFKRFLAHIANYLRYLQPMHTLD---DVLVMCSPFGL---ENF 196

Human   235 LNTLSCGVLSNVAG--PLLLTDARCLP-GTEGGGVFTARPAGALVALVVAPLCWKAGEWVGFTLL 296
            ..|:|.|.:|||.|  ..|...:..|| |.||..||..:.  .||.:|:.....:..|.|..||
  Fly   197 YKTISIGKVSNVMGRSGCLFAISNALPLGCEGSAVFNNKL--RLVGIVICTSFQRHHENVNLTL- 258

Human   297 CAAAPLFRAARDALHRLPHSTAALAALLPPEVGVPWGLPLRDSGPLWAAAAVLVECGTVWGSGVA 361
              ||......|:.:.:|..||.|......|            |...|....|::|.....|:|..
  Fly   259 --AANFGYLLRNFMEQLGMSTTAFQLSREP------------SSFAWERTIVVIESAGQQGTGTF 309

Human   362 VA---PRLVVTCRHVSPREAARVLVRSTTP--KSVAIWGRVVFATQETC------PYDIAVVSLE 415
            :.   .|.::||.||..:....|..|:...  :|..||          |      |:|:|:::..
  Fly   310 IRVHNKRFILTCAHVVGQNIETVNCRAADREFQSEVIW----------CNPDSDKPFDLALLTAP 364

Human   416 EDLDD--------VPIPVPAEHFHEGEAVSVVGFGV-----FGQSCGPSVTSGILSAVVQVNGTP 467
            :|:.:        .|..|       |:.|...||..     |.....||:..|   .|::.:...
  Fly   365 QDVPEQCCVRLARSPATV-------GQMVYNAGFPYYVNFSFRHDFNPSIFQG---RVIKCDTGA 419

Human   468 VMLQTTCAVHSGSSGGPLFSNHSGNLLGIITSNTRDNNTGATYPHLNFSIPITVLQPALQQYSQT 532
            :|  :..:|.:|.||||:| :.:|.:||:..||.:.::  ..||::|.:|||..::..|||:::|
  Fly   420 IM--SDGSVQAGQSGGPMF-DQNGCILGVCVSNIKLDD--VVYPNINTAIPICDIRNTLQQFART 479

Human   533 QDLGGLRELDRAAEP-VRVVWRLQRPLAEAP-RSKL 566
            .||..|..|  .|.| |..||.|:.|    | ||||
  Fly   480 NDLNVLSNL--VASPDVHRVWSLEMP----PIRSKL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TYSND1	NP_775826.2	Trypsin_2	357..496	CDD:433149	38/162 (23%)
CG3589	NP_611968.1	Trypsin_2	305..445	CDD:433149	38/162 (23%)