DRSC/TRiP Functional Genomics Resources

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Protein Alignment TMEM26 and CG14238

DIOPT Version :10

Sequence 1:NP_848600.2 Gene:TMEM26 / 219623 HGNCID:28550 Length:368 Species:Homo sapiens
Sequence 2:NP_651480.1 Gene:CG14238 / 43195 FlyBaseID:FBgn0039429 Length:523 Species:Drosophila melanogaster


Alignment Length:376 Identity:126/376 - (33%)
Similarity:191/376 - (50%) Gaps:68/376 - (18%)


- Green bases have known domain annotations that are detailed below.


Human     7 LNALATRLLFLLHSLVGVWRVTEVKKEPRYWLLALLNLLLFLETALTLKFKRGRGYKWFSPAIFL 71
            :.|:.||::|..|||:.:|:|..:|.:..||.|....|||.||...|:..|:.:.::||.|::||
  Fly     8 IKAILTRIIFSAHSLLAIWQVVALKSDIIYWALCGPLLLLLLEGIFTIMIKKTQEWRWFCPSVFL 72

Human    72 YLISIVPSLWLLELHHETQYCSIQAEGTSQNTSRKEDFNQ-----------TLTSNEQTSRADDL 125
            ||.||||::|||||....:..   ...||.|::.....|.           |.|::........|
  Fly    73 YLSSIVPAIWLLELDKVARRV---GNMTSTNSTVYSPSNYSIPVGNTTIFITSTNSSGVPPVATL 134

Human   126 IETAKVFVNNLSTVCEKVWTLGLHQTFLLMLIIGRWLLPIGGGITRDQLSQLLLMFVGTAADILE 190
            :..|.|.:    :|....||..:.|..:|:||:|||||| .|.:||||||||||:::||||||:|
  Fly   135 LGQAGVTL----SVTPDTWTTLIEQFLMLILIVGRWLLP-KGDLTRDQLSQLLLVYIGTAADIIE 194

Human   191 FTSETLEEQNVRNSPALVYAILVIWTWSMLQFPLDLAV---------------------QNVVCP 234
            | .::.::.::.....||:..|.||:||::||.:.|:.                     ||..|.
  Fly   195 F-FDSYKDDSIAKIGFLVFLTLGIWSWSLMQFTIVLSATRGRRPRGSGSHHKEEHTDCCQNCCCG 258

Human   235 VSVTERGFPSLFFCQYSADLWNIGISVFIQDGPFLVVRLILMTYFKVINQMLVFFAAKNFLVVVL 299
            :                 |:|.|.::|.:||.|||..||:::..:|:||.|.|||..||.||::|
  Fly   259 I-----------------DVWGIVLNVILQDAPFLTFRLLIIFQYKIINYMNVFFTCKNSLVIIL 306

Human   300 QLYRLVVLALAVRASLRSQSEGLKGEHGCRAQTSESGPSQRDWQNESKEGL 350
            |||||.|:          .:|..|.....|...|....|:|..|:..:..:
  Fly   307 QLYRLYVV----------NAEFWKNRRESRMAKSRQFQSRRKVQDADQNSI 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TMEM26NP_848600.2 Tmem26 3..303 CDD:430813 115/327 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 324..368 5/27 (19%)
CG14238NP_651480.1 Tmem26 4..310 CDD:430813 115/327 (35%)

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