Protein Alignment FARSA and PheRS-m

DIOPT Version :10

• Sequence 1: NP_004452.1
• Gene: FARSA / 2193
• HGNCID: 3592
• Length: 508
• Species: Homo sapiens
• Sequence 2: NP_477283.1
• Gene: PheRS-m / 36547
• FlyBaseID: FBgn0275436
• Length: 453
• Species: Drosophila melanogaster
• Alignment Length: 380
• Identity: 80/380 - (21%)
• Similarity: 139/380 - (36%)
• Gaps: 126/380 - (33%)

Human   168 VTLKT----YWVSKGSAFSTSISKQETELSPEMIS-SGS------WRDRPFKPYNFLAHGVLPDS 221
            :||:.    :|:......::|.:..::..||..:. |||      |.:...|..:::.     .:
  Fly     3 LTLRVQGARHWLKSTRCLASSAAPAKSPSSPPQLEVSGSTYATDGWTNVTPKILSYVG-----AN 62

Human   222 GHL---HPLLKVRSQFRQIFL-----EMG---FTEMPTDNFIESSFWNFDALFQPQQHPARDQHD 275
            .||   |||..:|.:....|.     :.|   |:.....|.:.:...|||.|..|..|.:|.:.|
  Fly    63 KHLQTDHPLSIIRQRIVNYFYGAYRNQRGNPLFSVYDQMNPVVTVQQNFDNLLIPADHVSRQKSD 127

Human   276 TFFLRDPAEALQLPMDYVQRVKRTHSQGGYGSQGYKYNWKLDEARKNLLRTHTTSASARALYRLA 340
            .:::.                                       :::|||.|||:.....:....
  Fly   128 CYYIN---------------------------------------QQHLLRAHTTAHQVELISGGL 153

Human   341 QKKPFTPVKYFSIDRVFRNETLDATHLAEFHQIE-------------------------GVVADH 380
            .       .:..:..|:|.:.:|:||...|||.:                         |.:||.
  Fly   154 D-------NFLVVGEVYRRDEIDSTHYPVFHQADAVRLVTKDKLFERNPGLELFEETWSGTLADP 211

Human   381 GLTLG------------HLMGV--LREFFTK---LGITQLRFKP--------AYNPYTEPSMEVF 420
            .|.|.            |.:..  |.|...|   :|:|:..|.|        .|.|:|:||.|:.
  Fly   212 KLILPSSKFMDQTKQPCHTLEAVKLMEHEMKHVLVGLTKDLFGPRIKYRWVDTYFPFTQPSWELE 276

Human   421 SYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGLSLERPTMIKYGINNIR 475
            .|.:  ..|:||...|:.|.|:|...|:.:::. .|:|:.|||..|:.:.|.:||
  Fly   277 IYFK--DNWLEVLGCGIMRHEILQRSGVHQSIG-YAFGVGLERLAMVLFDIPDIR 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FARSA	NP_004452.1	PTZ00326	1..484	CDD:240361	80/380 (21%)
PheRS-m	NP_477283.1	pheS_mito	29..452	CDD:129561	76/354 (21%)