Protein Alignment Nkx2-1 and bap

DIOPT Version :9

• Sequence 1: XP_011242403.1
• Gene: Nkx2-1 / 21869
• MGIID: 108067
• Length: 423
• Species: Mus musculus
• Sequence 2: NP_732637.1
• Gene: bap / 42537
• FlyBaseID: FBgn0004862
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 323
• Identity: 89/323 - (27%)
• Similarity: 119/323 - (36%)
• Gaps: 112/323 - (34%)

Mouse    54 MSPKHTTPFSVSDILS----------------------PLEESYKKVGMEGGGLGAPLAAYR--- 93
            :|...|||||::|||:                      |..:..:.:..........|..|:
  Fly    16 LSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRERSISKSPPLCCRDLGLYKLTQ 80

Mouse    94 ----QGQAAPPAAAMQQHAV-----GHHGAVTAAYHMTAAGVPQLSHSAVGG---------YCNG 140
                |..|..|:..:|.:|.     .||...|...:.:||...|...:..|.         .|..
  Fly    81 PKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAADYMQRKLAYFGSTLAAPLDMRRCTS 145

Mouse   141 NLGNMSELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMA 205
            |..:....||...:                   |:.|......||::
  Fly   146 NDSDCDSPPPLSSS-------------------PSESPLSHDGSGLS------------------ 173

Mouse   206 PLPSAPRRKR-RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKR 269
                  |:|| |..||.|||:||||||.||:|||.|||..:|..:.||.|||||||||.|||.||
  Fly   174 ------RKKRSRAAFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKR 232

Mouse   270 QAKDKAAQQQLQQDSGGGGGGGGGAGCPQQQQAQQQSPRRVAVPVLVK-DGKPCQAGAPAPGA 331
                    :|:|                |.:.|...:.:||.|.|||: ||....|...||||
  Fly   233 --------KQIQ----------------QHEAALLGASKRVPVQVLVREDGSTTYAHMAAPGA 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nkx2-1	XP_011242403.1	Homeobox	215..269	CDD:395001	36/54 (67%)
bap	NP_732637.1	Homeobox	178..231	CDD:278475	35/52 (67%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0842
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810