| Sequence 1: | NP_004094.3 | Gene: | PTK2B / 2185 | HGNCID: | 9612 | Length: | 1009 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_524743.2 | Gene: | Shark / 44353 | FlyBaseID: | FBgn0015295 | Length: | 939 | Species: | Drosophila melanogaster |
| Alignment Length: | 313 | Identity: | 113/313 - (36%) |
|---|---|---|---|
| Similarity: | 167/313 - (53%) | Gaps: | 31/313 - (9%) |
- Green bases have known domain annotations that are detailed below.
|
Human 386 ARRSHLSESCSIESDIYAEIPDETLRRPGGP----------QYGIAREDVVLNRILGEGFFGEVY 440
Human 441 EGVYTNHKG----EKINVAVKTCKKDCTLDNKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWII 501
Human 502 MELYPYGEL-------GHYLERNKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVAS 559
Human 560 PECVKLGDFGLSRYIE--DEDYYKASVTRLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFG 622
Human 623 KQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTEL 675 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PTK2B | NP_004094.3 | FERM_N_2 | 39..137 | CDD:436229 | |
| B41 | 41..254 | CDD:214604 | |||
| FERM_C_FAK1 | 261..368 | CDD:270011 | |||
| PTKc_FAK | 418..687 | CDD:133187 | 105/271 (39%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 701..725 | ||||
| Interaction with TGFB1I1. /evidence=ECO:0000250 | 801..1009 | ||||
| Focal adhesion targeting (FAT) | 868..1009 | ||||
| Focal_AT | 872..1001 | CDD:460992 | |||
| Shark | NP_524743.2 | SH2_Nterm_shark_like | 8..91 | CDD:198210 | |
| ANKYR | <94..317 | CDD:440430 | |||
| ANK repeat | 124..151 | CDD:293786 | |||
| ANK repeat | 153..184 | CDD:293786 | |||
| ANK repeat | 186..217 | CDD:293786 | |||
| ANK repeat | 220..245 | CDD:293786 | |||
| SH2_Cterm_shark_like | 287..395 | CDD:198211 | |||
| PTKc_Syk_like | 666..926 | CDD:270650 | 101/260 (39%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||