Protein Alignment ACSL3 and CG11391

DIOPT Version :9

• Sequence 1: NP_001341087.1
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Sequence 2: NP_650830.1
• Gene: CG11391 / 42353
• FlyBaseID: FBgn0038732
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 602
• Identity: 140/602 - (23%)
• Similarity: 219/602 - (36%)
• Gaps: 188/602 - (31%)

Human    60 VNSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIF 124
            :|..|.::|..|..       ::.||         :::...|:.|. ..:::..:.:.||. :||
  Fly     4 LNGNPATSYDPVQK-------VWSGC---------SRHSLYNEELT-VGQIIFRQLQRQPQ-RIF 50

Human   125 KKVILGQYNWLSYED--------VFVRAFNFGNGLQMLGQKPKTN-IAIFCETRAEWMIAAQACF 180
            :         :|:.|        :...|...|..|:..|.|.:|: :.:...........|..|
  Fly    51 Q---------ISHTDNTRLTRFQMLQNAAKIGCYLRDQGFKKETDLVGLMARNSTHVGALAYGC- 105

Human   181 MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELL------------QTKLKDIVSLVPRLRH 233
            ::|          |.|  .||:|.....|.|:|...:            ..|:|||.:.:..|
  Fly   106 LFN----------GTP--FHAVNPNLEHNTISSLYKITRPRILCCDTADYEKIKDIGASLGAL-- 156

Human   234 IITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSD------------IAVIMY 286
            ||||:||.|       |:|  ::|.:        ::|     |||.|            ...|:.
  Fly   157 IITVNGKLP-------GVI--SVADI--------LQN-----PLPDDYEPAQFQRGVDRTMAILC 199

Human   287 TSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGY 351
            :||:||.||.|.:|:|.      .:.|....||.:||..
  Fly   200 SSGTTGTPKAVTLSNSR------KLFEMHSYLGSDDVQY-------------------------- 232

Human   352 SSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYK 416
             :|.||...:..|             ||:.|.      ::..|....|||.|....|.|...:..
  Fly   233 -APSTLDWLTGLI-------------TLVTAA------VFGTVRLISSEMFSTAHFLDICEQHEV 277

Human   417 MEQISKGRNTPL---CDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQG---- 474
            ...|....:..:   |.....:|:|||.    .||..||..|.||.::..:...    |.|
  Fly   278 SWTIMANSHVAMLANCPKTSAQKLRSLK----HLLFAGGHCLVATLKKMQSFLH----GSGILRN 334

Human   475 -YGLTESAGAGTISEVWDYNT-------GRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIG 531
             |||||   .||:.. ::|:|       ||:.|     .|::|..:..|  ....|...||||..
  Fly   335 AYGLTE---VGTLVS-YNYDTQSKPTSVGRLMA-----NIRVKIVDSSG--QLQGPKGLGEILCH 388

Human   532 GQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGK 596
            ......||..|...|.    |..:...|..|||:|.|:.|..|.|::||||::|.....|.. .:
  Fly   389 NGQPWSGYVGNPLATA----EMRDSAGWYHTGDVGYFDEDHYLHIVERKKDMLKYLGMMYYP-HE 448

Human   597 VEAALKNLPLVDNICAY 613
            ||..:..:|.|..:|.:
  Fly   449 VEEVIAQMPDVAEVCVF 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL3	NP_001341087.1	AFD_class_I	30..717	CDD:418409	140/602 (23%)
CG11391	NP_650830.1	CaiC	24..541	CDD:223395	134/566 (24%)
		AFD_class_I	51..527	CDD:302604	128/537 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149093
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840