Protein Alignment ACSL3 and CG4830

DIOPT Version :10

• Sequence 1: NP_004448.2
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Sequence 2: NP_650160.1
• Gene: CG4830 / 41477
• FlyBaseID: FBgn0037996
• Length: 534
• Species: Drosophila melanogaster
• Alignment Length: 532
• Identity: 115/532 - (21%)
• Similarity: 185/532 - (34%)
• Gaps: 129/532 - (24%)

Human   113 EEDEVQPNGKIFKKVILGQYNW--------------LSYEDVFVRAFNFGNGLQMLGQKPKTNIA 163
            :.:..:|...:.:.:.....||              :::......|......|:..|...|..|.
  Fly    20 QNNPFKPETSLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQALTWAIRIAQQLKSRGLDHKDIIG 84

Human   164 IFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLV 228
            |........|..|.|||.:.....:....|....:.|..|.::...|.|..:..........:..
  Fly    85 ISARNTTYIMPTAVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFTDADHYDKLYSATSAFK 149

Human   229 PRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPL---PSDIAVIMYTSGS 290
            |.:  |:|...|        .|::     :::.|.|....|......||   ||....|:.:||:
  Fly   150 PEI--ILTTGTK--------DGVL-----SIQDLLAPTKTEFFYQPTPLKEGPSQTVAILTSSGT 199

Human   291 TGLPKGVMISHSNIIAGITGMAERIPELGEEDVYI-GY------LPLAHVLELSAELVCLSHGCR 348
            ||:||.|.||:.              .|.:|.|:: ||      ..|..:..|.|.:....:||.
  Fly   200 TGMPKAVCISND--------------ILTQETVFVNGYDTIFISASLDWITGLWATIFSTVNGCT 250

Human   349 IGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPE----IMDRIYKNVMNKVSEMSSFQRNLF 409
            ...||....||....:       .|....|.....||    ::|
  Fly   251 RIISSKPFAADYFVYL-------VSKYSITYALIPPEHCCSLLD--------------------- 287

Human   410 ILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQG 474
                               |.:....|    ||...:|...||....||.:|...:.....:...
  Fly   288 -------------------CPTATPEK----LGSLTKLNFGGGRMTQATVERVKKLAPNGVLNSS 329

Human   475 YGLTESAGAGTISEVWDYNTGRV-----GAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQS 534
            ||:||   .|.|.    :|.|.:     |.||...::|:.: ::|.....::   .|||::....
  Fly   330 YGMTE---VGFIV----FNHGHLKLTAAGNPLPGIQVKIVD-DDGNQLGVNQ---TGEIIVHNGF 383

Human   535 VTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEA 599
            ...||:.:...|||  .:||.|  |..|||:|.|:.|..|.:.||||:::|.: |..:...:|||
  Fly   384 SWNGYFADPEATKA--MQDEEG--WFHTGDMGYFDEDDYLYMTDRKKEVLKWK-GLQMWPAEVEA 443

Human   600 ALKNLPLVDNIC 611
            .:..||.|..:|
  Fly   444 VIDELPEVKRVC 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL3	NP_004448.2	Adenylate forming domain, Class I superfamily	30..717	CDD:473059	115/532 (22%)
CG4830	NP_650160.1	Firefly_Luc_like	46..518	CDD:341237	112/506 (22%)