Protein Alignment ACSL3 and CG5568

DIOPT Version :9

• Sequence 1: NP_001341087.1
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Sequence 2: NP_647992.1
• Gene: CG5568 / 38658
• FlyBaseID: FBgn0035641
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 134/566 - (23%)
• Similarity: 212/566 - (37%)
• Gaps: 150/566 - (26%)

Human   116 EVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACF 180
            :::.|..:..::.:.:...|:::|:...|....:.::.||.:....:.:...........|.|||
  Fly    46 QMERNAMLTAQISVTENTELTWKDIQTNAMKVASYMRKLGLEQGDFVGVIGRLTTHLTALAYACF 110

Human   181 MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLV-PRLRHIITVDGKPPTW 244
             :|          |.|  .|||:          .|..|:.::.:..:. |||   |..||
  Fly   111 -FN----------GTP--YHALH----------TEYEQSAIERLFGITKPRL---IFCDG----- 144

Human   245 SEFPKGIIVHTMAAVEALGAK-ASMENQP----------------HSKPL-----PSDIAVIMYT 287
            .||.|     ..||.:.|..: .:|.|.|                :.:|:     ...:..|:.:
  Fly   145 DEFEK-----VQAATKGLQVQIVTMRNHPAGILRIQDILTTPVEMNFRPVRLKDGTDQLLAILSS 204

Human   288 SGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYS 352
            ||::||||.|.||:|:.|.|                  .:||:...:              |.|
  Fly   205 SGTSGLPKAVTISNSHQIIG------------------SFLPVDSSI--------------IQY- 236

Human   353 SPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQ-RNL--FILAYN 414
            :|.|| |.:|.|..           |:.|||..         :..:.|...|. .||  .|..|.
  Fly   237 NPNTL-DWASGITM-----------TINAAVFS---------LTSIIEDCDFDPANLCGLIEKYR 280

Human   415 YKMEQISKGRNTPL--CDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQ-----RFMNICFCCPVG 472
            ..|..:|..:...|  |..|....:.|     ::....||:..|...|     |..|.|    |.
  Fly   281 ISMVFVSSSQLAMLSNCPEFYAADLSS-----VKYFFYGGSNCSLEVQNKIRSRLSNEC----VN 336

Human   473 QGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTM 537
            ..|.|||....|.::..:|.....||.|:...:||:.| |.|   ....|:..|||.........
  Fly   337 FSYTLTELNSPGCLNFNFDEKPNSVGRPVRGIQIKIVN-ELG---EAQGPNVVGEICFNNGQKWP 397

Human   538 GYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALK 602
            |||||..:||    :.::.:.|..|||:|..:.||.|.||||.||::|.|...|.. .::|:.:.
  Fly   398 GYYKNPEETK----KMQDSENWFHTGDLGYMDEDGYLFIIDRLKDMLKYQTIMYYP-SEIESVIA 457

Human   603 NLPLVDNICAYA---NSYHSYVIGFVVPNQ------KELTELARKK 639
            .:|.|...|.:.   ..|.......||..|      :::.|..||:
  Fly   458 EMPNVVEACVFGIWDPVYGDKAAASVVKKQGTQLEAQDVVEYVRKR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL3	NP_001341087.1	AFD_class_I	30..717	CDD:418409	134/566 (24%)
CG5568	NP_647992.1	CaiC	35..540	CDD:223395	134/566 (24%)
		Firefly_Luc_like	55..530	CDD:213279	133/557 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149087
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840