Protein Alignment ACSL3 and CG8834

DIOPT Version :9

• Sequence 1: NP_001341087.1
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Sequence 2: NP_610779.1
• Gene: CG8834 / 36356
• FlyBaseID: FBgn0033733
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 578
• Identity: 130/578 - (22%)
• Similarity: 207/578 - (35%)
• Gaps: 127/578 - (21%)

Human   112 NEEDEVQPNGK----------IFKKVILGQYNW--------------LSYEDVFVRAFNFGNGLQ 152
            ||:|.:....|          :.|.:.....||              :::|.....:......|:
  Fly     9 NEKDNIWSGAKRNSIYNYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIAQYLK 73

Human   153 MLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELL 217
            ..|...|..|.|..:.....|....||.|......::...|....:.|..:.|:.|.|....:..
  Fly    74 KRGLNHKDVIGIAAKNSTYVMPLGVACLMNGTPFHSVNPVLDDATLTHVFSITKPTLIFCDGQEY 138

Human   218 QTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMEN--QPHSKPLPSD 280
            ....|..|...|.:.          |.::..:|:     ..:|.|....:.|.  ||.......|
  Fly   139 DKVHKATVGWHPEIL----------TLTDHVEGV-----QGIETLLDPTTTEKIYQPEVLKEGGD 188

Human   281 IAV-IMYTSGSTGLPKGVMISHSNIIAG---ITGMAERIPELGEEDVYIGYLPLAHVLELSAELV 341
            ..| |:.:||:|||||.|.||:|.:|..   ||         .:..:|:|.. |..:..|.|.:.
  Fly   189 QTVAILCSSGTTGLPKAVCISNSILIQDSMLIT---------SQSVIYVGSC-LDWITGLWAFVF 243

Human   342 CLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQR 406
            ....||....|:.....:....:.|..|.:.::|.|..::|:....|.       |...::.
  Fly   244 STVFGCTRIISNKAFTPEYFVGLVKKYKINYAVLPPRHLSALITCPDA-------KPDALAP--- 298

Human   407 NLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPV 471
               |...||.                         ||:|.|         ||.||...:|.....
  Fly   299 ---ITHLNYG-------------------------GGSISL---------ATLQRSQELCKTAMF 326

Human   472 GQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEG---GYFNTDKPHPRGEILIGGQ 533
            ..|||:|| .||.||: :...|....|.|:...:|::.: |:|   ||      :..|||.:...
  Fly   327 NSGYGMTE-VGAITIN-IGISNVSSAGRPVPGIKIRIVD-EDGKSLGY------NQVGEIYVHTG 382

Human   534 SVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVE 598
            ....|||.|..:|:.  .:|..|  |..|||:|.|:....|.|:||||:::|.....|... ::|
  Fly   383 QAWNGYYGNPVETRR--MQDFEG--WFHTGDLGYFDEQNFLYIVDRKKEILKYNGLHYWPT-EIE 442

Human   599 AALKNLPLVDNICAYA--NSYHSYVIGFVVPNQKELTELARK------KGLKGTWEEL 648
            ..:..|..|.::|...  :.......|.:|...|..|..|::      |.|..|.::|
  Fly   443 TVIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATISAKEIVEHVAKRLPATQKQL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL3	NP_001341087.1	AFD_class_I	30..717	CDD:418409	130/578 (22%)
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	126/567 (22%)
		AFD_class_I	46..519	CDD:302604	123/541 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149094
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840